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Publication Date:
June 2005
ISSN:
1437-4315
DOI:
10.1515/BC.2001.169

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Biological Chemistry

Editor-in-Chief: Brüne, Bernhard

Editorial Board Member: Ludwig, Stephan / Sies, Helmut / Stoffel, Markus / Turk, Boris / Wittinghofer, Alfred / Baumeister, Wolfgang / Bergeron, John / Bogyo, Matthew / Bürkle, Alexander / Cadenas, Enrique / Chiti, Fabrizio / Dikic, Ivan / Dobson, Christopher / Driessen, Arnold / Fritz, Hans / Gevaert, Kris / Hammann, Christian / Hartl, F. Ulrich / Häussinger, Dieter / Hiscott, John / Igarashi, Yasuyuki / Klotz, Lars-Oliver / Krüger, Achim / Magdolen, Viktor / Müschen, Markus / Narumiya, Shuh / Naumann, Michael / Pejler, Gunnar / Pfanner, Nikolaus / Pike, Robert / Potempa, Jan / Saftig, Paul / Sandhoff, Konrad / Schaffner, Walter / Sinning, Irmgard / Sommerhoff, Christian P.

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Specific Nucleoprotein Complexes within Adenovirus Capsids

T. Dobner / D. Büchner / T. Zeller / H. Wolf / H.H. Niller

Citation Information: Biological Chemistry. Volume 382, Issue 9, Pages 1373–1377, ISSN (Print) 1431-6730, DOI: 10.1515/BC.2001.169, June 2005

Publication History:
Published Online:
2005-06-01

Abstract

Adenoviral DNA was examined within capsids by dimethyl sulfate footprinting. ProteinDNA interactions were visualized through ligationmediated PCR (LMPCR). Signals for protein binding were found adjacent to both inverted terminal repeats (ITR). There were no indications of close protein binding at several other loci of the viral genome. Therefore, adenovirus type 5 seems to contain sequence or locusspecific DNA binding proteins within the virion.

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