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The occurrence of Pneumocystis jirovecii in people from three different age groups of Warsaw (Poland) community

1Department of Medical Parasitology, National Institute of Hygiene, 24 Chocimska Str., 00-791, Warsaw, Poland

2Department of Epidemiology, National Institute of Hygiene, 24 Chocimska Str., 00-791, Warsaw, Poland

3Department of Virology, National Institute of Hygiene, 24 Chocimska Str., 00-791, Warsaw, Poland

© 2008 W. Stefański Institute of Parasitology, PAS. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. (CC BY-NC-ND 3.0)

Citation Information: Acta Parasitologica. Volume 53, Issue 1, Pages 106–109, ISSN (Online) 1896-1851, ISSN (Print) 1230-2821, DOI: 10.2478/s11686-008-0003-1, April 2008

Publication History

Published Online:
2008-04-07

Abstract

The three age groups of people from Warsaw: children, young adults and elderly people were examined for the prevalence of infection with Pneumocystis jirovecii. Nested PCR was used to amplify fragment of mitochondrial large subunit rRNA of the fungus in samples of oropharyngeal swabs. Nineteen (12.8%) of the 148 examined samples were positive for DNA of P. jirovecii. The samples collected from children were more often positive than the samples from young adults (p = 0.003) or from both groups of adults (p = 0.0029). Moreover, among adults (n = 99) proportion of infected women (n = 6; 12.5%) was significantly higher than men (n = 1; 2%). Results of the research confirm the high prevalence of Pneumocystis infection in children and indirectly point out to children as a possible source of infection for older people.

Keywords: Pneumocystis jirovecii; prevalence; age groups

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