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Biological Chemistry

Editor-in-Chief: Brüne, Bernhard

Editorial Board Member: Buchner, Johannes / Ludwig, Stephan / Sies, Helmut / Turk, Boris / Wittinghofer, Alfred

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Import of Carrier Proteins into Mitochondria

Kaye N. Truscott / Nikolaus Pfanner

Citation Information: Biological Chemistry. Volume 380, Issue 10, Pages 1151–1156, ISSN (Print) 1431-6730, DOI: 10.1515/BC.1999.146, June 2005

Publication History

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Carrier proteins located in the inner membrane of mitochondria are responsible for the exchange of metabolites between the intermembrane space and the matrix of this organelle. All members of this family are nuclear-encoded and depend on translocation machineries for their import into mitochondria. Recently many new translocation components responsible for the import of carrier proteins were identified. It is now possible to describe a detailed import pathway for this class of proteins. This review highlights the contribution made by translocation components to the process of carrier protein import into mitochondria.

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