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Biological Chemistry

Editor-in-Chief: Brüne, Bernhard

Editorial Board Member: Buchner, Johannes / Ludwig, Stephan / Sies, Helmut / Turk, Boris / Wittinghofer, Alfred

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Molecular Cloning and Characterization of a cDNA Encoding a Transferrin Homolog from Bombyx mori

Eun Young Yun / Seok Woo Kang / Jae Sam Hwang / Tae Won Goo / Sang Hyun Kim / Byung Rae Jin / O-Yu Kwon / Keun Young Kim

Citation Information: Biological Chemistry. Volume 380, Issue 12, Pages 1455–1459, ISSN (Print) 1431-6730, DOI: 10.1515/BC.1999.188, June 2005

Publication History:
Published Online:
2005-06-01

Abstract

We isolated a cDNA representing a message that was strongly induced by injection with E. coli in Bombyx mori. The 2160 bp cDNA has an open reading frame of 644 amino acids and the deduced product a predicted molecular mass of 71 kDa. The cDNA sequence shared high homology with the transferrins known so far, and its deduced peptide had unique features of transferrins, that is, sites of cystein residues and iron binding. We suggest that the B. mori transferrin plays an important role in the self-defense system.

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