Jump to ContentJump to Main Navigation

Biological Chemistry

Editor-in-Chief: Brüne, Bernhard

Editorial Board Member: Buchner, Johannes / Ludwig, Stephan / Sies, Helmut / Turk, Boris / Wittinghofer, Alfred

12 Issues per year



Apoptotic Pathways: Involvement of Lysosomal Proteases

B. Turk / V. Stoka / J. Rozman-Pungercar / T. Cirman / G. Droga-Mazovec / K. Oreic / V. Turk

Citation Information: Biological Chemistry. Volume 383, Issue 7-8, Pages 1035–1044, ISSN (Print) 1431-6730, DOI: 10.1515/BC.2002.112, June 2005

Publication History

Published Online:


Apoptosis or programmed cell death is the major mechanism used by multicellular organisms to remove infected, excessive and potentially dangerous cells. Cysteine proteases from the caspase family play a crucial role in the process. However, there is increasing evidence that lysosomal proteases are also involved in apoptosis. In this review various lysosomal proteases and their potential contribution to propagation of apoptosis are discussed.

Comments (0)

Please log in or register to comment.