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Publication Date:
October 2006
ISSN:
1862-278X
DOI:
10.1515/BMT.2006.031

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Biomedical Engineering / Biomedizinische Technik

Editor-in-Chief: Dössel, Olaf

Editorial Board Member: Augat, Peter / Bösiger, Peter / Gehring, Hartmut / Haueisen, Jens / Leonhardt, Steffen / Niederlag, Wolfgang / Radermacher, Klaus M. / Schmitz, Georg / Witte, Herbert / Boenick, Ulrich / Lenthe, Harry / Penzel, Thomas / Clasbrummel, Bernhard / Robitzki, Andrea A. / Scholz, Jörg / Snedeker, Jess G. / Wintermantel, Erich / Jockenhoevel, Stefan / Gilly, Hermann / Werner, Jürgen / Plank, Gernot / Stieglitz, Thomas

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Non-linear dynamic analysis of the cardiac rhythm during transient myocardial ischemia

Pedro Gomis1 / Pere Caminal2 / Montserrat Vallverdú3 / Stafford Warren4 / Galen Wagner5

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Corresponding author: Pedro Gomis, PhD, Technical University of Catalonia, Pau Gargallo, 5, Edif U, 08028 Barcelona, Spain Phone: +34-93-4010763 Fax: +34-93-4017045

Citation Information: Biomedizinische Technik. Volume 51, Issue 4, Pages 178–181, ISSN (Online) 1862-278X, ISSN (Print) 0013-5585, DOI: 10.1515/BMT.2006.031, October 2006

Publication History:
Published Online:
2006-10-25

Abstract

Coronary artery occlusions related to myocardial ischemia drive cardiac control system reactions that may lead to heart failure. The purpose of this study was to assess the autonomic nervous system (ANS) response during prolonged percutaneous transluminal coronary angioplasty (PTCA). Continuous ECG data were acquired from 50 patients before and during PTCA, with occlusions in the left anterior descending, left circumflex or right coronary artery. Heart rate variability (HRV) was analyzed for 3-min segments of the R-R interval signal obtained from ECG data. The ANS behavior was evaluated by HRV analysis using fractal-like indices. The fractal scalar exponent α1 and power-law slope β decreased considerably during PTCA. This indicates that significant reactions of autonomic control of the heart rate occurred during coronary artery occlusions, with a reduction in complexity of the ANS.

Keywords: angioplasty; cardiac ischemia; complex systems; fractal analysis; heart rate variability

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