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Publication Date:
June 2005
ISSN:
1437-4331
DOI:
10.1515/CCLM.2000.176

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Clinical Chemistry and Laboratory Medicine (CCLM)

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Determination of Decision Limits for ACS:Systems Cardiac Troponin I

Franca Pagani / Graziella Bonetti / Francesca Stefini / Claudio Cuccia / Mauro Panteghini

Citation Information: Clinical Chemistry and Laboratory Medicine. Volume 38, Issue 11, Pages 1155–1157, ISSN (Print) 1434-6621, DOI: 10.1515/CCLM.2000.176, June 2005

Publication History:
Published Online:
2005-06-01

Abstract

The availability of specific markers of myocardial damage has focused attention on the decision limits to be used in clinical practice. These markers can be employed in the diagnosis of myocardial infarction and risk stratification in patients with acute coronary syndromes but no infarction. The measurement of troponin I was undertaken in two 60 patient cohorts with these disease classifications. The best decision level for patients with acute myocardial infarction was found to be 3.1 μgl; for the detection of minimal myocardial damage the cut-off was equal to the detection limit of the method (0.2 μgl).

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