Abstract

Serum protein analysis has been the primary focus of the laboratories at the Foundation for Blood Research (FBR) since 1965. Designed by clinicians to assist in the diagnosis and management of their patients, the Foundation's serum protein analyses became tools to answer questions that were difficult or impossible to answer at the bedside or by traditional chemistry tests. Research on the subject quickly led to services that required computer assistance. Measurement of individual proteins expanded as need dictated and finances allowed. Serum protein electrophoresis was added as a necessary test early in the process. Research, expansion of the number of test offered, and test volumes have demanded automation of both testing and interpretation. Testing now includes assays of 15 serum proteins, serum iron, and autoantibodies and is tailored to meet the needs of general practitioners, pediatricians, several internal medical specialties, and paramedical personnel. Samples rather than patients are sent to the laboratory and reports are returned by mail or electronic means. Physicians review all complex reports.