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Publication Date:
June 2005
ISSN:
1437-4331
DOI:
10.1515/CCLM.2001.179

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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the International Federation of Clinical Chemistry and Laboratory Medicine and the European Federation of Clinical Chemistry and Laboratory Medicine

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The Existing Interim Consensus Reference Ranges and the Future Approach

Francesco Dati / A. Myron Johnson / John T. Whicher

Citation Information: Clinical Chemistry and Laboratory Medicine. Volume 39, Issue 11, Pages 1134–1136, ISSN (Print) 1434-6621, DOI: 10.1515/CCLM.2001.179, June 2005

Publication History:
Published Online:
2005-06-01

Abstract

The release of the reference material for serum proteins, CRM 470/RPPHS, in 1993, has given rise to a great improvement in the between-laboratory variability of serum protein measurements worldwide. However, conversion to the new reference material has resulted in significant changes in reference values for some proteins. The establishment of new reference ranges is currently in progress; in the interim, several professional societies and diagnostic companies have agreed to use consensus reference ranges based on studies that were already undertaken.

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