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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Schlattmann, Peter / Tate, Jillian R. / Tsongalis, Gregory J.

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The IFCC recommendation on estimation of reference intervals. The RefVal Program

Helge Erik Solberg

Citation Information: Clinical Chemistry and Laboratory Medicine. Volume 42, Issue 7, Pages 710–714, ISSN (Print) 1434-6621, DOI: 10.1515/CCLM.2004.121, June 2005

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The International Federation of Clinical Chemistry (IFCC) published between 1987–91 a series of six recommendations on reference values in laboratory medicine. This paper reviews the history and scope of the fifth part of these recommendations. This fifth recommendation deals with statistical methods used for analysis of reference values and estimation of reference intervals. The RefVal program, which implements the recommended method, is also described.

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