Jump to ContentJump to Main Navigation

Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Editorial Board Member: Gillery, Philippe / Kazmierczak, Steven / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Schlattmann, Peter / Whitfield, John B.

12 Issues per year

40% increased IMPACT FACTOR 2012: 3.009
Rank 5 out of 31 in category Medical Laboratory Technology in the 2012 Thomson Reuters Journal Citation Report/Science Edition



Proposal for guidelines to establish common biological reference intervals in large geographical areas for biochemical quantities measured frequently in serum and plasma

Pål Rustad / Peter Felding / Ari Lahti

Citation Information: Clinical Chemistry and Laboratory Medicine. Volume 42, Issue 7, Pages 783–791, ISSN (Print) 1434-6621, DOI: 10.1515/CCLM.2004.131, June 2005

Publication History:
Published Online:


A suggestion for a standard procedure to establish biological reference intervals for biochemical quantities by a multicenter approach is presented. This procedure was developed for and used in the Nordic Reference Interval Project 2000 (NORIP). This project established biological reference intervals for 25 frequently requested biochemical quantities through cooperation of 102 Nordic laboratories. Each laboratory performed collection of reference samples and measurement using their routine methods. The bias of each routine method was eliminated by use of common reference materials measured in each of the participating laboratories.

Comments (0)

Please log in or register to comment.
Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.