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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Schlattmann, Peter / Tate, Jillian R. / Tsongalis, Gregory J.

13 Issues per year

IMPACT FACTOR 2013: 2.955
Rank 5 out of 29 in category Medical Laboratory Technology in the 2013 Thomson Reuters Journal Citation Report/Science Edition

SCImago Journal Rank (SJR): 0.860
Source Normalized Impact per Paper (SNIP): 1.046



New biomarkers for acute renal injury

Sachin S. Soni1, 2 / Rupesh Pophale3 / 4

1Manik Hospital and Research Centre, Aurangabad, India

2Assistant Professor in Nephrology, MGM Medical College, Aurangabad, India

3JJ Hospital, Mumbai, India

4Department of Nephrology, Dialysis and Transplantation, International Renal Research Institute, Vicenza (IRRIV), Italy

Corresponding author: Claudio Ronco, MD, Director, Department of Nephrology Dialysis and Transplantation, International Renal Research Institute Vicenza (IRRIV), San Bortolo Hospital, Viale Rodolfi, 37, 36100 Vicenza, Italy Phone: +39 0444 753869, Fax: +39 0444 753949

Citation Information: Clinical Chemistry and Laboratory Medicine. Volume 49, Issue 8, Pages 1257–1263, ISSN (Online) 1437-4331, ISSN (Print) 1434-6621, DOI: 10.1515/CCLM.2011.664, July 2011

Publication History

Published Online:


Incidence of acute kidney injury (AKI) is increasing rapidly to epidemic proportions. Development of AKI, especially in intensive care settings, is associated with increased morbidity, mortality and hospitalization costs. Currently available diagnostic tools are mostly insensitive for early diagnosis, however prompt diagnosis and risk stratification are necessary for guiding therapy and preventing progression of disease. Finding an early, reliable, suitable, easily reproducible, economical and accurate biomarker for AKI is a top research priority. In recent years, many urinary and serum proteins have been investigated as possible early markers of AKI and some of them have shown great promise. This topic reviews some of the emerging biomarkers of AKI.

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