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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Editorial Board Member: Gillery, Philippe / Kazmierczak, Steven / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Schlattmann, Peter / Whitfield, John B.

12 Issues per year

40% increased IMPACT FACTOR 2012: 3.009
Rank 5 out of 31 in category Medical Laboratory Technology in the 2012 Thomson Reuters Journal Citation Report/Science Edition



Volume 52, Issue 5 (May 2014)


Page i

Published Online: 04/03/2014



Epigenetic mechanisms in bone

Vrtačnik, Peter / Marc, Janja / Ostanek, Barbara

Page 589

Published Online: 12/18/2013

Opinion Papers

Hepcidin levels in chronic hemodialysis patients: a critical evaluation

Valenti, Luca / Messa, Piergiorgio / Pelusi, Serena / Campostrini, Natascia / Girelli, Domenico

Page 613

Published Online: 11/14/2013

D-dimer testing for suspected venous thromboembolism in the emergency department. Consensus document of AcEMC, CISMEL, SIBioC, and SIMeL

Lippi, Giuseppe / Cervellin, Gianfranco / Casagranda, Ivo / Morelli, Benedetto / Testa, Sophie / Tripodi, Armando

Page 621

Published Online: 10/24/2013

General Clinical Chemistry and Laboratory Medicine

Effect of biobanking conditions on short-term stability of biomarkers in human serum and plasma

Zander, Johannes / Bruegel, Mathias / Kleinhempel, Alisa / Becker, Susen / Petros, Sirak / Kortz, Linda / Dorow, Juliane / Kratzsch, Jürgen / Baber, Ronny / Ceglarek, Uta / Thiery, Joachim / Teupser, Daniel

Page 629

Published Online: 12/11/2013

Non-invasive detection of fetal trisomy 21 using fetal epigenetic biomarkers with a high CpG density

Lim, Ji Hyae / Lee, Da Eun / Kim, Kyeong Sun / Kim, Hyun Jin / Lee, Bom Yi / Park, So Yeon / Ahn, Hyun Kyong / Lee, Si Won / Kim, Moon Young / Ryu, Hyun Mee

Page 641

Published Online: 12/18/2013

Development and validation of dried matrix spot sampling for the quantitative determination of amyloid β peptides in cerebrospinal fluid

Delaby, Constance / Gabelle, Audrey / Meynier, Philippe / Loubiere, Vincent / Vialaret, Jérôme / Tiers, Laurent / Ducos, Jacques / Hirtz, Christophe / Lehmann, Sylvain

Page 649

Published Online: 10/23/2013

Instability of cerebrospinal fluid after delayed storage and repeated freezing: a holistic study by drop coating deposition Raman spectroscopy

Klener, Jakub / Hofbauerová, Kateřina / Bartoš, Aleš / Říčný, Jan / Řípová, Daniela / Kopecký, Vladimír

Page 657

Published Online: 11/30/2013

Analysis of patients with γ-heavy chain disease by the heavy/light chain and free light chain assays

Kaleta, Erin / Kyle, Robert / Clark, Raynell / Katzmann, Jerry

Page 665

Published Online: 12/11/2013

Performance of urinary NGAL and L-FABP in predicting acute kidney injury and subsequent renal recovery: a cohort study based on major surgeries

Zeng, Xian-Fei / Li, Jun-Min / Tan, Yun / Wang, Zhu-Feng / He, Yong / Chang, Jiang / Zhang, Hong / Zhao, Hua / Bai, Xiao / Xie, Fei / Sun, Juan / Zhang, Yan

Page 671

Published Online: 11/29/2013

Rapid extraction, identification and quantification of drugs of abuse in hair by immunoassay and ultra-performance liquid chromatography tandem mass spectrometry

Pichini, Simona / Gottardi, Massimo / Marchei, Emilia / Svaizer, Fiorenza / Pellegrini, Manuela / Rotolo, Maria Concetta / Algar, Oscar García / Pacifici, Roberta

Page 679

Published Online: 11/28/2013

Validity and reliability of the 13C-methionine breath test for the detection of moderate hyperhomocysteinemia in Mexican adults

Maldonado-Hernández, Jorge / Prina-Ojeda, Laura Virginia / Montalvo-Velarde, Irene / Del Prado-Manríquez, Martha / de Lourdes Barbosa-Cortés, María / Repetto-Madrid, Mariana

Page 687

Published Online: 03/07/2014

Quantitative detection of target cells using unghosted cells (UGCs) of DxH 800 (Beckman Coulter)

Lee, Wonbae / Kim, Jung-Ho / Sung, In Kyung / Park, Sung Kyun / Oh, Seong Taek / Park, Hun-Hee / Park, Yeon-Joon / Kim, Yonggoo / Oh, Eun-Jee / Kim, Myungshin / Park, Hae-Il / Han, Kyungja

Page 693

Published Online: 12/05/2013

Evaluation of different sized blood sampling tubes for thromboelastometry, platelet function, and platelet count

Andreasen, Jo Bønding / Pistor-Riebold, Thea Unger / Knudsen, Ingrid Hell / Ravn, Hanne Berg / Hvas, Anne-Mette

Page 701

Published Online: 12/05/2013

Cancer Diagnostics

Routine use of the Ion Torrent AmpliSeq™ Cancer Hotspot Panel for identification of clinically actionable somatic mutations

Tsongalis, Gregory J. / Peterson, Jason D. / de Abreu, Francine B. / Tunkey, Christopher D. / Gallagher, Torrey L. / Strausbaugh, Linda D. / Wells, Wendy A. / Amos, Christopher I.

Page 707

Published Online: 12/13/2013

Analytical performance of a new one-step quantitative prostate-specific antigen assay, the FREND™ PSA Plus

Park, Hae-il / Lee, Seungok / Kim, Yonggoo / Shin, Dong-Yeok / Lee, Changseop / Han, Sunmi / Chung, Chanil / Chang, Jun Keun / Seo, In Bum

Page 715

Published Online: 12/07/2013

Relationship between prostate-specific antigen kinetics and detection rate of radiolabelled choline PET/CT in restaging prostate cancer patients: a meta-analysis

Treglia, Giorgio / Ceriani, Luca / Sadeghi, Ramin / Giovacchini, Giampiero / Giovanella, Luca

Page 725

Published Online: 12/05/2013

Methylation of OPCML promoter in ovarian cancer tissues predicts poor patient survival

Zhou, Feng / Tao, Guohua / Chen, Xiang / Xie, Wei / Liu, Manhua / Cao, Xingjian

Page 735

Published Online: 12/11/2013

Cardiovascular Diseases

Red blood cell distribution width predicts survival in patients with Eisenmenger syndrome

Yang, Tao / Sun, Yun-Juan / Xiong, Chang-Ming / Zeng, Wei-Jie / Ni, Xin-Hai / Zhao, Zhi-Hui / Liu, Zhi-Hong / Gu, Qing / He, Jian-Guo

Page 743

Published Online: 12/06/2013

Low serum adropin is associated with coronary atherosclerosis in type 2 diabetic and non-diabetic patients

Wu, Lingzhen / Fang, Jun / Chen, Lianglong / Zhao, Ziwen / Luo, Yukun / Lin, Chaogui / Fan, Lin

Page 751

Published Online: 12/09/2013


Standardization and analytical goals for glycated hemoglobin measurement

Braga, Federica / Panteghini, Mauro

Page 759

Published Online: 04/03/2014

Letter to the Editors

Do we need to worry about contamination by circulating fetal DNA?

Wu, Hai / Huang, Gengming / Romay-Penabad, Zurina / Pierangeli, Silvia / Dong, Jianli

Page e75

Published Online: 12/18/2013

Aldosterone measurement with LiaisonXL automated system: remarks about reference range

Fortunato, Antonio / Marchetti, Cristina / Pinaffo, Giulia Francesca

Page e85

Published Online: 12/13/2013

Better blood collection tubes for plasma glucose: ready for prime time?

Szoke, Dominika / Valente, Cristina / Panteghini, Mauro

Page e87

Published Online: 01/09/2014

Upregulation of cytokines and IL-17 in patients with hereditary angioedema

Arcoleo, Francesco / Salemi, Marilisa / La Porta, Antonio / Selvaggio, Valentina / Mandalà, Vitalba / Muggeo, Vito / Misiano, Gabriella / Milano, Salvatore / Romano, Giuseppina Colonna / Cillari, Enrico

Page e91

Published Online: 01/08/2014

Underestimation of platelet count on magnesium salt-anticoagulated samples

François, Dominique / Masure, Anne / Atallah, Norma / Touil, Lynda / Vasse, Marc

Page e95

Published Online: 12/19/2013

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