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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Schlattmann, Peter / Tate, Jillian R. / Tsongalis, Gregory J.

14 Issues per year

IMPACT FACTOR 2014: 2.707
Rank 6 out of 30 in category Medical Laboratory Technology in the 2014 Thomson Reuters Journal Citation Report/Science Edition

SCImago Journal Rank (SJR) 2014: 0.741
Source Normalized Impact per Paper (SNIP) 2014: 1.011
Impact per Publication (IPP) 2014: 2.310



Volume 53, Issue 12 (Nov 2015)


Page i

Published Online: 11/04/2015


Biomarkers of inflammatory bowel disease: ready for prime time?

Plebani, Mario / Basso, Daniela / Lippi, Giuseppe

Page 1881

Published Online: 10/14/2015


Discriminant indices for distinguishing thalassemia and iron deficiency in patients with microcytic anemia: a meta-analysis

Hoffmann, Johannes J.M.L. / Urrechaga, Eloísa / Aguirre, Urko

Page 1883

Published Online: 05/12/2015

Mini Reviews

Cell-free DNA for diagnosing myocardial infarction: not ready for prime time

Lippi, Giuseppe / Sanchis-Gomar, Fabian / Cervellin, Gianfranco

Page 1895

Published Online: 04/17/2015

The Laboratory Medicine and the care of patients infected by the Ebola virus. Experience in a reference hospital of Madrid, Spain

Fernandez-Puntero, Belen / Gomez-Rioja, Ruben / Alcaide, Maria Jose / Oliver, Paloma / Fernandez-Calle, Pilar / Iturzaeta, Jose Manuel / Buno, Antonio

Page 1903

Published Online: 06/06/2015

Opinion Papers

Theranos phenomenon − part 2

Li, Michelle / Diamandis, Eleftherios P.

Page 1911

Published Online: 09/24/2015

Considerations in parathyroid hormone testing

Cavalier, Etienne / Plebani, Mario / Delanaye, Pierre / Souberbielle, Jean-Claude

Page 1913

Published Online: 06/02/2015

Quantity quotient reporting. Comparison of various models

Haeckel, Rainer / Wosniok, Werner / Postma, Theo

Page 1921

Published Online: 05/12/2015

Genetics and Molecular Diagnostics

Assessing quality and functionality of DNA isolated from FFPE tissues through external quality assessment in tissue banks

Ahmad-Nejad, Parviz / Duda, Angelika / Sucker, Antje / Werner, Martin / Bronsert, Peter / Stickeler, Elmar / Reifenberger, Guido / Malzkorn, Bastian / Oberländer, Martina / Habermann, Jens K. / Bruch, Hans-Peter / Linnebacher, Michael / Schadendorf, Dirk / Neumaier, Michael

Page 1927

Published Online: 06/06/2015

Influence of storage conditions and extraction methods on the quantity and quality of circulating cell-free DNA (ccfDNA): the SPIDIA-DNAplas External Quality Assessment experience

Malentacchi, Francesca / Pizzamiglio, Sara / Verderio, Paolo / Pazzagli, Mario / Orlando, Claudio / Ciniselli, Chiara Maura / Günther, Kalle / Gelmini, Stefania

Page 1935

Published Online: 04/17/2015

Non-invasive fetal ABO genotyping in maternal plasma using real-time PCR

Song, Wenqian / Zhou, Shihang / Shao, Linnan / Wang, Ni / Pan, Lingzi / Yu, Weijian

Page 1943

Published Online: 06/12/2015

Screening non-deletion α-thalassaemia mutations in the HBA1 and HBA2 genes by high-resolution melting analysis

Petropoulou, Margarita / Poula, Amalia / Traeger-Synodinos, Jan / Vrettou, Christina / Kanavakis, Emmanuel / Christopoulos, Theodore K. / Ioannou, Penelope C.

Page 1951

Published Online: 06/02/2015

General Clinical Chemistry and Laboratory Medicine

European views on patients directly obtaining their laboratory test results

Watson, Ian D. / Siodmiak, Joanna / Oosterhuis, Wytze P. / Corberand, Joel / Jorgensen, Per E. / Dikmen, Zeliha Gunnur / Jovicic, Snezana / Theodorsson, Elvar / for the EFLM Working Group on Patient Focused Laboratory Medicine

Page 1961

Published Online: 06/03/2015

Diagnostic performances of clinical laboratory tests using Triton X-100 to reduce the biohazard associated with routine testing of Ebola virus-infected patients

Tempestilli, Massimo / Pucci, Luigia / Notari, Stefania / Caro, Antonino Di / Castilletti, Concetta / Rivelli, Maria Rosaria / Agrati, Chiara / Pucillo, Leopoldo Paolo

Page 1967

Published Online: 06/06/2015

Thrombin generation, D-dimer and protein S in uncomplicated pregnancy

Kovac, Mirjana K. / Lalic-Cosic, Sanja Z. / Dmitrovic, Jelena M. / Djordjevic, Valentina J. / Radojkovic, Dragica P.

Page 1975

Published Online: 05/06/2015

Multi-analyte analysis of non-vitamin K antagonist oral anticoagulants in human plasma using tandem mass spectrometry

Blaich, Cornelia / Müller, Carsten / Michels, Guido / Wiesen, Martin H.J.

Page 1981

Published Online: 04/22/2015

Second generation analysis of antinuclear antibody (ANA) by combination of screening and confirmatory testing

Scholz, Juliane / Grossmann, Kai / Knütter, Ilka / Hiemann, Rico / Sowa, Mandy / Röber, Nadja / Rödiger, Stefan / Schierack, Peter / Reinhold, Dirk / Bogdanos, Dimitrios P. / Meroni, Pier Luigi / Radice, Antonella / Conrad, Karsten / Roggenbuck, Dirk

Page 1991

Published Online: 05/15/2015

Faecal leukocyte esterase activity is an alternative biomarker in inflammatory bowel disease

Dumoulin, Els N. / Van Biervliet, Stephanie / De Vos, Martine / Himpe, Jonas / Speeckaert, Marijn M. / Delanghe, Joris R.

Page 2003

Published Online: 04/17/2015

Reference Values and Biological Variations

Total folate and 5-methyltetrahydrofolate in the cerebrospinal fluid of children: correlation and reference values

Akiyama, Tomoyuki / Tada, Hiroko / Shiokawa, Tsugumi / Kobayashi, Katsuhiro / Yoshinaga, Harumi

Page 2009

Published Online: 05/05/2015

Effect of age and gender on reference intervals of red blood cell distribution width (RDW) and mean red cell volume (MCV)

Hoffmann, Johannes J.M.L. / Nabbe, Karin C.A.M. / van den Broek, Nicole M.A.

Page 2015

Published Online: 05/09/2015

Infectious Diseases

Inosine triphosphate pyrophosphohydrolase activity: more accurate predictor for ribavirin-induced anemia in hepatitis C infected patients than ITPA genotype

Peltenburg, Nicole Chantal / Bakker, Jaap A. / Vroemen, Wim H.M. / de Knegt, Robert J. / Leers, Mathie P.G. / Bierau, Jörgen / Verbon, Annelies

Page 2021

Published Online: 05/13/2015

The ratio of calprotectin to total protein as a diagnostic and prognostic marker for spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

Lutz, Philipp / Pfarr, Kenneth / Nischalke, Hans Dieter / Krämer, Benjamin / Goeser, Felix / Glässner, Andreas / Wolter, Franziska / Kokordelis, Pavlos / Nattermann, Jacob / Sauerbruch, Tilman / Hoerauf, Achim / Strassburg, Christian P. / Spengler, Ulrich

Page 2031

Published Online: 06/02/2015

Letter to the Editors

Misleading high-sensitivity troponin algorithm for NSTEMI in the ESC guidelines

Zur, Berndt / Stoffel-Wagner, Birgit

Page e323

Published Online: 11/04/2015

Adjustment of serum potassium for age and platelet count. A simple step forward towards personalized medicine

Lippi, Giuseppe / Salvagno, Gian Luca / Guidi, Gian Cesare

Page e325

Published Online: 06/02/2015

The impact of Tween 20 on repeatability of amyloid β and tau measurements in cerebrospinal fluid

Toombs, Jamie / Paterson, Ross W. / Nicholas, Jennifer M. / Petzold, Axel / Schott, Jonathan M. / Zetterberg, Henrik

Page e329

Published Online: 06/23/2015

Effect of storage time and temperature on the generation of reactive oxygen species in peripheral blood leukocytes

Chang, Yu-Chien / Lo, Wen-Jyi / Huang, Yu-Ting / Lin, Chaio-Lin / Cheng, Hsu-Chen / Yeh, Su-Peng

Page e333

Published Online: 06/02/2015

A functional variant in the γ-glutamyltransferase (GGT)1 gene is associated with airflow obstruction in smokers

Morita, Kazunori / Masuda, Natsuki / Tanaka, Takahiro / Saruwatari, Junji / Oniki, Kentaro / Kajiwara, Ayami / Otake, Koji / Ogata, Yasuhiro / Nakagawa, Kazuko

Page e339

Published Online: 06/17/2015

Creatinine, Jaffe, and glucose: another inconvenient truth

Weykamp, Cas / Kuypers, Aldy / Bakkeren, Dirk / Franck, Paul / Loon, Douwe van / Gunnewiek, Jacqueline Klein / Jonge, Robert de / Steigstra, Herman / Cobbaert, Christa

Page e347

Published Online: 05/21/2015

Analytical evaluation of a new liquid immunoturbidimetric assay for the determination of ferritin in serum

Molinario, Rossana / Autilio, Chiara / Pocino, Krizia / Daloiso, Pio Dante / Di Leva, Salvatore / Zuppi, Cecilia / Antenucci, Mirca

Page e351

Published Online: 06/18/2015

Analytical assessment of the novel homocysteine liquid enzymatic assay on Beckman Coulter AU5800

Dipalo, Mariella / Dipietro, Martina / Gnocchi, Cecilia / Musa, Roberta / Aloe, Rosalia / Lippi, Giuseppe

Page e355

Published Online: 06/23/2015

Immunoglobulin IgA, IgD, IgG, IgM and IgG subclass reference values in adults

Puissant-Lubrano, Bénédicte / Peres, Michael / Apoil, Pol-André / Congy-Jolivet, Nicolas / Roubinet, Francis / Blancher, Antoine

Page e359

Published Online: 01/30/2015

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