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International Journal of the Biology, Chemistry, Physics, and Technology of Wood

Editor-in-Chief: Faix, Oskar

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Antifungal diterpenes from the bark of Cryptomeria japonica D. Don

Hisayoshi Kofujita1 / Youji Fujino2 / Michikazu Ota3 / Kouetsu Takahashi4





Corresponding author. Hisayoshi Kofujita, Faculty of Agriculture, Iwate University, Ueda 3-18-8, Morioka 020-8550, Japan Tel./Fax: +81-19-621-6171

Citation Information: Holzforschung. Volume 60, Issue 1, Pages 20–23, ISSN (Online) 1437-434X, ISSN (Print) 0018-3830, DOI: 10.1515/HF.2006.004, January 2006

Publication History

September 6, 2005
October 20, 2005
Published Online:


Bioassay-guided isolation of compounds from n-hexane extracts of the bark of Cryptomeria japonica resulted in six abietane- and two pimarane-type diterpenoids, including a new compound, 12-methoxy-6α,11-dihydroxyabieta-8,11,13-triene. The structure of the new substance was established by spectral analyses and comparison with related compounds. The antifungal activities of these diterpenes were evaluated against the phytopathogenic fungi Alternaria alternata, Pyricularia oryzae, Rhizoctonia solani and Fusarium oxysporum. The diterpenes showed moderate antifungal activity against the fungi examined.

Keywords: abietane; antifungal activity; Cryptomeria japonica; diterpene; pimarane

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