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The International Journal of Biostatistics

Ed. by Hubbard, Alan E. / van der Laan, Mark J.

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Principal Stratification -- a Goal or a Tool?

Judea Pearl1

1University of California, Los Angeles

Citation Information: The International Journal of Biostatistics. Volume 7, Issue 1, Pages 1–13, ISSN (Online) 1557-4679, DOI: 10.2202/1557-4679.1322, March 2011

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Principal stratification has recently become a popular tool to address certain causal inference questions, particularly in dealing with post-randomization factors in randomized trials. Here, we analyze the conceptual basis for this framework and invite response to clarify the value of principal stratification in estimating causal effects of interest.

Keywords: causal inference; principal stratification; surrogate endpoints; direct effect; mediation

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