Cell growth and recombinant phytase production under the control of the GAP promoter were studied in continuous cultivation experiments of Pichia pastoris. Based on these studies, a simple kinetic model was established to predict biomass and enzyme production. Although parameters were mainly estimated using the results of continuous cultivation, the proposed model was able to successfully predict cell growth and phytase production in three different fed-batch cultivations of P. pastoris using limited glucose feeding.
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- A Review of Rapid Gas-Solid Separation Techniques
- Recent Achievements in Combination of Ultrasonolysis and Other Advanced Oxidation Processes for Wastewater Treatment
- Non-Ideal Flow in Liquid-Solid Fixed Beds of Irregular-Shaped Particles: A Critical Review
- A Review of the Water Gas Shift Reaction Kinetics
- Control of Reactive Distillation Column: A Review
- Modeling of Fluid Catalytic Cracking Riser Reactor: A Review
- 6-Lump Kinetic Model for a Commercial Vacuum Gas Oil Hydrocracker
- On the Observability for a Class of Nonlinear (Bio)chemical Systems
- Modeling of Commercial Ethylene Oxide Reactor: A Hybrid Approach by Artificial Neural Network & Differential Evolution
- A Study of Direct Hydration of Dihydromyrcene to Dihydromyrcenol Using Cation Exchange Resins as Catalyst
- Modeling and Simulation of Ethylene and 1-Butene Copolymerization in Solution with a Ziegler-Natta Catalyst
- Modeling and Simulation of Industrial Continuous Naphtha Catalytic Reformer Accompanied with Delumping the Naphtha Feed
- Modeling of Phytase Production by Cultivation of Pichia pastoris Under the Control of the GAP Promoter
- An Experimental Study of the Coking Process
- Gas Hold-Up and Mass Transfer in Three Geometrically Similar Internal Loop Airlift Reactors Using Newtonian Fluids
- Two-Dimensional Simulations of Gas-Liquid Two-Phase Flow in Mini channels of PEM Fuel Cell Flow Field
- The Wall Layer Interactions in a Partially Heated Rectangular Enclosure
- Conversion of Biodiesel By-Product Glycerol to Fuel Ethers over Different Solid Acid Catalysts
- Approximate Solution of Time-Fractional Chemical Engineering Equations: A Comparative Study
- Conformation Studies of the Interaction of the Pest-Resistant Toxin from Bacillus thuringiensis with Brown and Red Soils
- Constrained Hybrid Neural Modelling of Biotechnological Processes
- Kinetics of Catalytic Thermal Pretreatment (Catalytic Thermolysis) of Distillery Wastewater and Bio-Digester Effluent of Alcohol Production Plant at Atmospheric Pressure
- Analysis of the Gas Holdup Evolution in a Circulating Jet-Loop Nitrifying MBR
- Heat Coupling of Gasoline Upgrading and Fluid Catalytic Cracking Processes
- Modeling and Simulation of Dissolved Oxygen Concentrations in a Full-Scale Textile Dyeing Wastewater Treatment Plant
- Validation of a 2D CFD Model for Hydrodynamics' Studies in CIJ Mixers
- Modelling of Physico-Chemical Phenomena between Gas inside a Bubble and Liquid Metal during Injection of Oxidant Gas
- Simulation and Optimization of Biodiesel Production by Soybean Oil Transesterification in Non-Ideal Continuous Stirred-Tank Reactor
- Simulation Studies of Steam Reforming of Methane using Ni-AlO Catalysts
- Gas-Solids Flow Properties of a Square Circulating Fluidized Bed with Secondary Air Injection
- CFD Simulation of the Effect of Monolith Wall Thickness on the Light off Performance of a Catalytic Converter
- On the Mathematical Modelling of Diffusion-Migration Mass Transport of Protons
- Friedel-Crafts Alkylation of Resorcinol over Mesoporous Alumina Loaded with Sulfuric Acid
- The CO Oxidation Mechanism Over Ag-Co And Co-Ce Mixed Oxide Catalysts
- Geometry Effects in Eulerian/Granular Simulation of a Turbulent FCC Riser with a (kg-?g)-KTGF Model
- Numerical Simulation of an Evaporative Spray in a Gas-Solid Crossflow
- Thermodynamic and Kinetic Analysis of Ca-Based Oxygen Carrier in Chemical-Looping Combustion
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- Separation and Hydrodynamic Performance of Air-Kerosene-Water System by Bubble Column
- Investigation of Light Tar Cracking in a Gliding Arc Plasma System
- Modelling of a Catalytic Micro-Reactor Coupling Endothermic Methane Reforming and Combustion
- Analysis of a Model for Ethanol Production through Continuous Fermentation: Ethanol Productivity
- Solids Flow Models for Gas - Flowing Solids - Fixed Bed Contactors
- Non-Similar Solutions for Heat and Mass Transfer from a Surface Embedded in a Porous Medium for Two Prescribed Thermal and Solutal Boundary Conditions
- Performance Study of Pervaporation Reactor (PVR) for Esterification of Acetic Acid with Ethanol
- Simulation of Supercritical Water Oxidation with Air at Pilot Plant Scale
- Enhanced Production of Ligninolytic Enzymes by Ganoderma lucidum IBL-06 Using Lignocellulosic Agricultural Wastes
- Kinetic Study on a Commercial Amorphous Hydrocracking Catalyst by Weighted Lumping Strategy
- Optimization of a Three-Phase Catalytic Slurry Reactor Using Reduced Statistical Models
- Enhancement of Brønsted Acidity in Sulfate-Vanadium Treated Silica-Titania Aerogel as Oxidative-Acidic Bifunctional Catalyst
- Enhancement of the Catalytic Performances in the Case of a Consecutive-Parallel Reaction Scheme
- Liquid-Phase Esterification of Methacrylic Acid with Methanol Catalyzed by Heteropolyacid
- Removal of Hydrogen Sulfide from Gas Stream Using a Novel Metal Membrane Prepared by Wire Arc Spraying
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- A New Integrated Photoreactor for Microwave Assisted Decolorization of Acid Orange 7 (AO7) in Aqueous Solutions
- Modeling a Delayed Coking Process with GRNN and Double-Chain Based DNA Genetic Algorithm
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- Catalyzed Decomposition of Methane into CO-free Hydrogen and Filamentous Carbons over NiO-CuO/SiO: Effect of NiO-CuO Loadings
- Development of a Kinetic Model for Modeling the Industrial VGO Hydrocracker Accompanied By Deactivation
- Exergoeconomic Optimization of Black Liquor Gasification Combined Cycle Using Evolutionary and Conventional Iterative Method
- Fenton's Process for Post-Biologically Treated Cheese Production Wastewaters Final Remediation. Toxicity Assessment
- Energy and Exergy Analysis of the Teduction Zone in a Downdraft (Biomass) Gasifier
- Methane Production during Start-Up Phase of Mesophilic Semi-Continues Suspended Growth Anaerobic Digester
- Prediction of Minimum Fluidization Velocity in Two-Phase and Three-Phase Fluidized Beds: Air/Newtonian and Non-Newtonian Liquids
- Optimization of a Marine Medium for Augmented Biosurfactant Production
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- Hydrodynamic Characterization of an Electrochemical Cell with Rotating Disc Electrode: A Three-Dimensional Biphasic Model
- Synthesis of Oxide Particles Using a Polymer-Assisted Spray Pyrolysis Reactor, and a Percolation Explanation of Particle Separation
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- New Approach to the Nonlinear Analysis of a Chemostat with Impulsive State Feedback Control
- Genetic Algorithms (Binary and Real Codes) for the Optimisation of a Fermentation Process for Butanol Production
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- Heat Transfer between Fluidized Bed and Horizontal Bundle of Tubes in a Vertical Channel
- Pathways of Amino Acid Transformation and Decomposition in Saturated Subcritical Water Conditions
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- Slurry Phase Reactor Technology for DME Direct Synthesis
- Analytical Solution of Linear and Non-Linear Space-Time Fractional Reaction-Diffusion Equations
- Operational Range for a Gas-Liquid-Solid Fluidized Bed Aerobic Biofilm Reactor with a Low-Density Biomass Support
- Mathematical Simulation of Solid-Liquid Diffusion in Continuous Countercurrent Extraction Process, Part I - Modeling Development
- Mathematical Simulation of Solid-Liquid Diffusion in Continuous Countercurrrent Extraction Process, Part II - Modeling Verification and Its Application
- Theoretical Analysis of a Flow-By Electrochemical Reactor with Porous Cathode for the Simultaneous Removal of Different Metal Ions
- Analysis of Ka Measurement Methods in Stirred Vessels: The Role of Experimental Techniques and Fluid Dynamic Models
- Mass Transfer Studies in a Novel Perforated Plate Bubble Column
- Gas-Newtonian and Gas-Non-Newtonian Slug Flow in Vertical Pipe, Part I: Gas Holdup Characteristics
- Axial Mixing in a Novel Perforated Plate Bubble Column
- Experimental Estimation of Fluidization Parameters - A Stochastic Approximation Method Approach
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- Ecological Optimization of Generalized Irreversible Chemical Engines
- Agglomeration of Bitumen-Coated Coke Particles in Fluid Cokers
- Correlation for Prediction of Minimum Fluidization Velocity and Riser Liquid Holdup in Three-Phase External Loop Air Lift Fluidized Bed Reactor
- Influence of Free Stream Turbulence Intensity on Heat Transfer and Flow Around Four In-Line Elliptic Cylinders in Cross Flow
- Hydrodynamic Studies on Zeolite Fluidized Beds
- Oxygen Mass Transfer Coefficients in a Three-Phase Pulsed Plate Bioreactor
- Improved Production of Bacillus thuringiensis by Intermittent Fed-Batch Culture with Total Cell Retention
- Simulation of Size Distributions of TiO Nanoparticles in a Propane/Air Flame
- Coke Formation Reduction in the Steam Cracking of Naphtha on Industrial Alloy Steels Using Sulfur-Based Inhibitors
- Enhanced Decolorization of NOVASOL Direct Black Textile Dye by Agaricus bitorqus A66
- Heat and Mass Transfer by MHD Stagnation-Point Flow of a Power-Law Fluid towards a Stretching Surface with Radiation, Chemical Reaction and Soret and Dufour Effects
- Retention of Cadmium and Zinc from Aqueous Solutions by Poly(acrylic Acid)-Assisted Ultrafiltration
- Flow Study and Wetting Efficiency of a Perforated-Plate Tray Distributor in a Trickle Bed Reactor
- Adsorption and Flotation of Soluble Crude Protein by Colloidal Gas Aphrons (CGA): Effect of Selected Variables and Process Modeling
- Adsorption of Bovine Serum Albumin onto Metal Oxides: Adsorption Equilibrium and Kinetics onto Alumina and Zirconia
- Hydrophilic and Hydrophobic Modifications of Microchannel Inner Walls for Liquid-Liquid Laminar Layered Flows
- Transesterification of Triolein with Methanol in Reactive Distillation Column: Simulation Studies
- Final Remediation of Post-Biological Treated Milk Whey Wastewater by Ozone
- Comparative Analysis of Biosorption Potential for Chromium Removal by Live and Dead Biomass of Aspergillus niger ZH2
- Influence of Irradiation on Fenton Degradation of Brilliant Red X-3B
- Fabrication and Super-Hydrophobicity of TiO Nanostructure with Urchin Shapes
- Electro Oxidation and Biodegradation of Textile Dye Effluent Containing Procion Blue 2G Using Fungal Strain Phanerochate Chrysosporium MTCC 787
- Automatic Control Design for Optimal Strategy in Fed-batch Culture with Coupled Feed of Glycerol and Alkali
- Experimental Study of Silica Nano-Powder Synthesis Using a Diffusion Flame Reactor
- Wet Hydrolysis of Waste Polyethylene Terephthalate Thermoplastic Resin with Sulfuric Acid and CFD Simulation for High Viscous Liquid Mixing
- Equilibrium and Kinetic Modelling of Astrazon Yellow Adsorption by Sawdust: Effect of Important Parameters
- Deposition of Evaporating Droplets in a Decelerating Boundary Layer with Wall Suction: Mathematical Analysis
- Photocatalytic Degradation of Eriochrome Black Dye in a Rotating Corrugated Drum Photocatalytic Reactor
- Negative Net CO Emissions from Oxy-Decarbonization of Biogas to H
- Thermodynamic Analysis for Gasification of Thailand Rice Husk with Air, Steam, and Mixed Air/Steam for Hydrogen-Rich Gas Production
- Simulation of Combustion Process and Soot Yield in Propane/Air Laminar Diffusion Flame by Self-Defined Scalar Method
- Photocatalytic Degradation of Formaldehyde in Gas Phase on TiO Films: A Kinetic Study
- Traveling Wave Solutions for MHD Aligned Flow of a Second Grade Fluid
- An Innovative Microwave Process for Nanocatalyst Synthesis
- Thermochemical Solar Reactor: Simplified Method for the Geometrical Optimization at a Given Incident Flux
- Characterisation of Tar produced in the Gasification of Biomass with in situ Catalytic Reforming
- Surfactant Aggregates in Ionic Liquids and Reactivity in Media
- Kinetics of Acid Hydrolysis of Arabinogalactans
- Dimethyl Ether Synthesis over Novel Silicotungstic Acid Incorporated Nanostructured Catalysts
- Fuel Gas Production by Gasification of Glycerol Waste over Perovskite-Type Oxide Catalysts
- Indoor Air Purification by Compost Packed Biofilter
- Development and Validation of a Steady-State Mathematical Model for the Physicochemical Processing of Biopolymers by Reactive Extrusion
- Enhanced Microwave Induced Thermochemical Conversion of Waste Glycerol for Syngas Production
- Use of Ash from Sewage Sludge in the Preparation of Desulfurant Sorbents
- Overview of Biorefineries based on Co-Production of Furfural, Existing Concepts and Novel Developments
- Cocoa Butter Saturated with Supercritical Carbon Dioxide: Measurements and Modelling of Solubility, Volumetric Expansion, Density and Viscosity
- Performance of Trickle Bed Reactor and Active Carbon in the Liquid Phase Oxidation of Phenol
- Hydrodynamic Behaviour and Mass Transfer Performance of SiC Foam
- Membrane Extraction of Penicillin G from a Synthetic Fermentation Media Using Sunflower Oil
- Greener and Sustainable Method for Alkene Epoxidations by Polymer-Supported Mo(VI) Catalysts
- Performance of Sludge Based Activated Carbons in Catalytic Wet Air Oxidation of Phenol
- Modeling Thermal Decomposition Kinetic Algorithms on CL-20 and HMX
- An Off-Lattice Flory-Huggins Approach of the Partitioning of Bulky Solutes between Polymers and Interacting Liquids
- Experimental Evaluation of Indirect Heating Tubular Reactors for Solar Methane Pyrolysis
- A TRNSYS Dynamic Simulation Model for Photovoltaic System Powering a Reverse Osmosis Desalination Unit with Solar Energy
- Fractal Law: A New Tool for Modelling Agglomeration Process
- Solid Pyrolysis Modelling by a Lagrangian and Dimensionless Approach--Application to Cellulose Fast Pyrolysis
- Influence of pH, Temperature and Impurities on the Solubility of an Active Pharmaceutical Ingredient (API)
- Development of a New Absorption-Demixing Heat Transformer: Cycle and Working Mixture Optimization
- Preparation of Composite Hydrogels for Medical Applications: Experimental Study and Modeling of Mass Transfers
- Use of a Heat Pump to Supply Energy to the Iodine-Sulphur Thermochemical Cycle for Hydrogen Production
- Optimization of Gas Transmission Networks under Energetic and Environmental Considerations
- Influence of Particle Size, Reactor Temperature and Gas Phase Reactions on Fast Pyrolysis of Beech Wood
- Study of the Behaviour of a Catalytic Ceramic Candle Filter in a Lab-Scale Unit at High Temperatures
- Bioenergy II: Tin Catalysed Esterification of Free Fatty Acids
- Bioenergy II: Modeling and Multi-Objective Optimization of Different Biodiesel Production Processes
- Bioenergy II: Characterization of the Pesticide Properties of Tobacco Bio-Oil
- Bioenergy II: Hydrogen Production by Aqueous-Phase Reforming
- Bioenergy II: Suitability of Wood Chips and Various Biomass Types for Use in Plant of BtL Production by Gasification
- Bioenergy II: Bio-Ethanol from Municipal Solid Waste (MSW): The Role of Biomass Properties and Structures During the Ethanol Conversion Process
- Bioenergy II: The Development of a Reactive Distillation Process for the Production of 1,1 Diethoxy Butane from Bioalcohol: Kinetic Study and Simulation Model
- Bioenergy II: Comparison of Laboratory and Industrial Saccharomyces cerevisiae Strains for their Stress Tolerance
- Experimental Study of a Novel Fast Gas-Solid Separator for Pyrolysis Reactors
- Cleaner Routes for Friedel-Crafts Acylation
- Biomass Sourcing and Logistics: From Theory to Practice
- Ionic Liquid-Aided Carboxymethylation of Kraft Pulp
- Synthesis and Characterization of Pt-Sn Incorporated MCM-41 and Pt Incorporated Sn-SiO Type Mesoporous Catalysts for Direct Ethanol Fuel Cell
- Toluene Combustion over Metal Oxide Washcoated Monolithic Catalyst
- Low Temperature Water-Gas Shift Reaction on Au-CeO/AlO Catalysts
- Electrochemical Performance of Low Pt and Ru Loaded Fe-Ni Bimetallics as an Anode Electrode in Direct Ethanol Fuel Cells
- FTIR Studies of Urea Decomposition over Pt-Alumina and Cu-Alumina Catalysts
- HZSM-5 and H-Ferrierite Acidity Modification by Silylation and Their Activities in n-Butene Isomerisation
- Production of Syngas by Combination of CO Reforming and Partial Oxidation of CH over Ni/AlO Catalysts in Fixed-bed Reactor
- Modelling Catalyst Deactivation by External Coke Deposition during Fluid Catalytic Cracking
- Cascade Control Scheme for Tubular Reactors with Multiple Temperature Measurements
- Effect of Gas Jet on Agglomeration of Inhalable Particles
- Microwave-Enhanced Alkali Catalyzed Transesterification of Kenaf Seed Oil
- Relation between Volumetric Mass Transfer Coefficient and Power Input per Unit Volume for Converging-Diverging Tube Airlift Fermenter
- Effects of AlCl-NaCl Content on the Formation of Mesocarbon Microbeads
- Removal of Zinc Ions from Water Using Emulsion Liquid Membrane
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Modeling of Phytase Production by Cultivation of Pichia pastoris Under the Control of the GAP Promoter
1University of Ottawa, stang047@uottawa.ca
2University of Ottawa, gpotvin@uottawa.ca
3University of Ottawa, areic028@uottawa.ca
4University of Ottawa, zzhang@uottawa.ca
Citation Information: International Journal of Chemical Reactor Engineering. Volume 8, Issue 1, Pages –, ISSN (Online) 1542-6580, DOI: 10.2202/1542-6580.2144, January 2010
Publication History:
- Published Online:
- 2010-01-19
Keywords: kinetic modeling; GAP promoter; continuous cultivation; Pichia pastoris
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