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Journal of Complementary and Integrative Medicine

Editor-in-Chief: Lui, Edmund

Ed. by Chan, Kelvin / Ko, Robert / Leung, Kelvin Sze-Yin / Tamayo, Carmen / Zhang, Zhang-Jin

4 Issues per year

SCImago Journal Rank (SJR) 2014: 0.203
Source Normalized Impact per Paper (SNIP) 2014: 0.290
Impact per Publication (IPP) 2014: 0.655

Iatrogenic venous thrombosis secondary to supplemental medicine toxicity

1Cleveland Clinic, Cleveland, OH, USA

2Wake Forest Baptist Medical Center, Winston-Salem, NC, USA

Citation Information: Journal of Complementary and Integrative Medicine. Volume 10, Issue 1, Pages 129–134, ISSN (Online) 1553-3840, ISSN (Print) 2194-6329, DOI: 10.1515/jcim-2012-0003, August 2013

Publication History

Published Online:


Objective: We described a case of cerebral venous sinus thrombosis in a patient taking multiple supplements as part of a naturopathic anti-aging regimen.

Methods: Case report.

Results: The patient presented with a thalamic infarct associated with a thrombus in the vein of Galen. He reported no previous history of endocrinopathy and no known hypercoagulability risk factors. He was treated with therapeutic anticoagulation resulting in improvement. Diagnostic workup revealed hyperthyroidism and gonadotrophic deficiency attributed to significant supplement medicine usage.

Conclusion: This case highlights a potential risk of dietary supplements. Use of these supplements may be a risk factor for idiopathic cerebral venous thrombosis.

Keywords: cerebral venous thrombosis,; hyperthyroidism,; gonadotropin deficiency

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