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Journal of Pediatric Endocrinology and Metabolism

Editor-in-Chief: Kiess, Wieland

Editorial Board Member: Darendeliler, Feyza / Gustafsson, Jan / Luo, Feihong / Mericq, Veronica / Lanes M. D., Roberto / Battelino, Tadej / Buyukgebiz, Atilla / Cassorla, Fernando / Chrousos, George P. / Cutfield, Wayne / Fideleff, Hugo L. / Hershkovitz, Eli / LaFranchi, Stephen H. / Mohn, Angelika / Root, Allen W. / Rosenfeld, Ron G. / Wabitsch, Martin / Werther, George / Zadik, Zvi

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Effects of a Structured Exercise Program on Insulin Resistance, Inflammatory Markers and Physical Fitness in Obese Korean Children

Hyun-Wook Chae1 / Yu-Na Kwon2 / Young-Jun Rhie3 / Ho-Seong Kim1 / Yu-Sik Kim2 / Il-Young Paik2 / Sang-Hoon Suh2 / Duk-Hee Kim1

1Department of Pediatrics, Yonsei University, Seoul, Korea

2Department of Physical Education, Yonsei University, Seoul, Korea

3Department of Pediatrics, Korea University College of Medicine, all of Seoul, Korea

Corresponding author: Sang-Hoon Suh,

Corresponding author: Duk-Hee Kim, MD,

Citation Information: Journal of Pediatric Endocrinology and Metabolism. Volume 23, Issue 10, Pages 1065–1072, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: 10.1515/jpem.2010.168, January 2010

ABSTRACT

Thirty-eight obese Korean children (21 boys, 17 girls), whose ages were between 9 and 15, were divided into either the intervention group (19 obese children: BMI>95P) or the age- and sex-matched obese control group. The intervention group performed an intensive exercise program under the supervision of educated instructors for 12 weeks (90 minutes/day, two days/week) and received lifestyle modification counseling using food diaries and phone calls. The control group participated in conventional counseling at an out-patient clinic. The intervention group appeared to have more improvement of body weight, body composition, serum lipid profiles and high-sensitivity C-reactive protein (hs-CRP) levels (P < 0.05) but without changes in serum adiponectin level. HOMA-IR decreased from 2.3 to 1.3 in the intervention group. Maximal oxygen consumption (VO2 max) and other physical fitness parameters were significantly improved after the intervention program (P < 0.05).

KEY WORDS: exercise; childhood obesity; insulin resistance; adiponectin; physical fitness

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