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Journal of Pediatric Endocrinology and Metabolism

Editor-in-Chief: Kiess, Wieland

Ed. by Bereket, Abdullah / Cohen, Pinhas / Darendeliler, Feyza / Dattani, Mehul / Gustafsson, Jan / Luo, Feihong / Mericq, Veronica / Roth, Christian / Toppari, Jorma

Editorial Board Member: Battelino, Tadej / Buyukgebiz, Atilla / Cassorla, Fernando / Chrousos, George P. / Cutfield, Wayne / Fideleff, Hugo L. / Hershkovitz, Eli / Hiort, Olaf / LaFranchi, Stephen H. / Lanes M. D., Roberto / Mohn, Angelika / Root, Allen W. / Rosenfeld, Ron G. / Werther, George / Zadik, Zvi


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Long Term Cereal-Based Nutritional Supplementation Improved the Total Spine Bone Mineral Density amongst Sri Lankan Preschool Children: A Randomized Controlled Study

Manjula Hettiarachchi1 / Sarath Lekamwasam2 / Chandrani Liyanage2

1Nuclear Medicine Unit, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka

2Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka

Corresponding Author: Manjula Hettiarachchi,

Citation Information: Journal of Pediatric Endocrinology and Metabolism. Volume 23, Issue 6, Pages 555–563, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: 10.1515/jpem.2010.094, September 2010

Publication History

Published Online:
2010-09-17

ABSTRACT

Background: The Thriposha programme in Sri Lanka provides a combination of energy, protein and micronutrients as a ‘ready-to-eat’ cereal-based food.

Objective: To assess the effectiveness of calcium and vitamin D3 in the Thriposha on bone mineralization among preschool children aged 3-5 years.

Design: Subjects (n=30) were fed with conventional Thriposha while the control group (n=30) children were fed without mineral and vitamin premix (Corn-Soya-Blend - CSB) for a period of nine months. Dual-energy X-ray absorptiometry (DXA) of total spine was measured at the baseline and after the intervention.

Results: The mean baseline total spine BMD was 0.464(0.050) g/cm2 in the interventional group and 0.453(0.035) g/cm2 in the control group (p=0.09). At the end of the study, the BMD levels were 0.487(0.047) and 0.454(0.031) g/cm2 (p<0.001) respectively.

Conclusion: Daily supplementation of cereal based food supplement over a period of nine months improved the total spine BMD.

KEY WORDS: Thriposha supplementation; calcium; vitamin D; bone mineral density; pre-school children

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[1]
Anuradha Khadilkar, Nidhi Kadam, Shashi Chiplonkar, Philip R. Fischer, and Vaman Khadilkar
Bone, 2012, Volume 51, Number 1, Page 1

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