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Journal of Pediatric Endocrinology and Metabolism

Editor-in-Chief: Kiess, Wieland

Ed. by Bereket, Abdullah / Cohen, Pinhas / Darendeliler, Feyza / Dattani, Mehul / Gustafsson, Jan / Luo, Feihong / Mericq, Veronica / Roth, Christian / Toppari, Jorma

Editorial Board Member: Battelino, Tadej / Buyukgebiz, Atilla / Cassorla, Fernando / Chrousos, George P. / Cutfield, Wayne / Fideleff, Hugo L. / Hershkovitz, Eli / Hiort, Olaf / LaFranchi, Stephen H. / Lanes M. D., Roberto / Mohn, Angelika / Root, Allen W. / Rosenfeld, Ron G. / Werther, George / Zadik, Zvi


IMPACT FACTOR 2015: 0.912

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2191-0251
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Insulin Resistance and the Metabolic Syndrome in Obese Children Referred to an Obesity Center

J. Rotteveel1 / A. Felius1 / M. M. van Weissenbruch1 / H. A. Delemarre–Van de Waal1

1Department of Pediatrics, VU University Medical Center, Amsterdam, and Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands

Corresponding author: J. Rotteveel,

Citation Information: Journal of Pediatric Endocrinology and Metabolism. Volume 23, Issue 9, Pages 943–951, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: 10.1515/jpem.2010.151, December 2010

Publication History

Published Online:
2010-12-22

ABSTRACT

Objective: The aim of this study was to describe insulin resistance and the metabolic syndrome in obese children and adolescents.

Subjects: The cohort consisted of 518 patients, 250 boys, 268 girls, age ± sd: 11.8 ± 3.2 years, BMIsds ± sd: 2.94 ± 0.5. A standard OGTT was performed.

Results: Impaired glucose tolerance was found in 9.4% of the boys and 5.5% of the girls. Impaired fasting glucose was found in 12.4% of the boys and 11.6% of the girls. The metabolic syndrome was present in 13.9% of children of 10 years or older. The proportion in which the metabolic syndrome was diagnosed was essentially not altered when pubertal groups were used instead of age groups.

Conclusion: Both impaired fasting glucose and impaired glucose tolerance as well as the metabolic syndrome are highly prevalent among obese children and adolescents.

KEY WORDS: obesity; metabolic syndrome; insulin resistance

Citing Articles

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[1]
B. Tobisch, L. Blatniczky, and L. Barkai
Pediatric Obesity, 2015, Volume 10, Number 1, Page 37
[2]
E Hagman, T Reinehr, J Kowalski, A Ekbom, C Marcus, and R W Holl
International Journal of Obesity, 2014, Volume 38, Number 1, Page 40
[3]
Rishi Gupta, Amrit Bhangoo, Nicole A.V. Matthews, Henry Anhalt, Yesu Matta, Basant Lamichhane, Shahid Malik, Shivinder Narwal, Graciela Wetzler, and Svetlana Ten
Journal of Pediatric Endocrinology and Metabolism, 2011, Volume 24, Number 11-12
[4]
Mehmet Emre Atabek
Journal of Pediatric Endocrinology and Metabolism, 2011, Volume 24, Number 7-8

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