Journal of Pediatric Endocrinology and Metabolism
Editor-in-Chief: Kiess, Wieland
Ed. by Bereket, Abdullah / Cohen, Pinhas / Darendeliler, Feyza / Dattani, Mehul / Gustafsson, Jan / Luo, Feihong / Mericq, Veronica / Roth, Christian / Toppari, Jorma
Editorial Board Member: Battelino, Tadej / Buyukgebiz, Atilla / Cassorla, Fernando / Chrousos, George P. / Cutfield, Wayne / Fideleff, Hugo L. / Hershkovitz, Eli / Hiort, Olaf / LaFranchi, Stephen H. / Lanes M. D., Roberto / Mohn, Angelika / Root, Allen W. / Rosenfeld, Ron G. / Werther, George / Zadik, Zvi
IMPACT FACTOR 2015: 0.912
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Insulin Resistance and the Metabolic Syndrome in Obese Children Referred to an Obesity Center
1Department of Pediatrics, VU University Medical Center, Amsterdam, and Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands
Citation Information: Journal of Pediatric Endocrinology and Metabolism. Volume 23, Issue 9, Pages 943–951, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: 10.1515/jpem.2010.151, December 2010
- Published Online:
Objective: The aim of this study was to describe insulin resistance and the metabolic syndrome in obese children and adolescents.
Subjects: The cohort consisted of 518 patients, 250 boys, 268 girls, age ± sd: 11.8 ± 3.2 years, BMIsds ± sd: 2.94 ± 0.5. A standard OGTT was performed.
Results: Impaired glucose tolerance was found in 9.4% of the boys and 5.5% of the girls. Impaired fasting glucose was found in 12.4% of the boys and 11.6% of the girls. The metabolic syndrome was present in 13.9% of children of 10 years or older. The proportion in which the metabolic syndrome was diagnosed was essentially not altered when pubertal groups were used instead of age groups.
Conclusion: Both impaired fasting glucose and impaired glucose tolerance as well as the metabolic syndrome are highly prevalent among obese children and adolescents.
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