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Journal of Pediatric Endocrinology and Metabolism

Editor-in-Chief: Kiess, Wieland

Editorial Board Member: Darendeliler, Feyza / Gustafsson, Jan / Luo, Feihong / Mericq, Veronica / Lanes M. D., Roberto / Battelino, Tadej / Buyukgebiz, Atilla / Cassorla, Fernando / Chrousos, George P. / Cutfield, Wayne / Fideleff, Hugo L. / Hershkovitz, Eli / LaFranchi, Stephen H. / Mohn, Angelika / Root, Allen W. / Rosenfeld, Ron G. / Wabitsch, Martin / Werther, George / Zadik, Zvi

12 Issues per year


IMPACT FACTOR 2013: 0.711

SCImago Journal Rank (SJR): 0.334
Source Normalized Impact per Paper (SNIP): 0.423

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Pros of priming in the diagnosis of growth hormone deficiency

1 / Alev Ozon1 / Ayfer Alikasifoglu1 / Nurgun Kandemir1

1Department of Pediatric Endocrinology, Hacettepe University Faculty of Medicine, Ankara, Turkey

Corresponding author: E. Nazli Gonc, Department of Pediatric Endocrinology, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey Phone: +903123051124, Fax: +903123121809

Citation Information: Journal of Pediatric Endocrinology and Metabolism. Volume 24, Issue 1-2, Pages 9–11, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: 10.1515/jpem.2011.076, March 2011

Publication History

Published Online:
2011-03-16

Abstract

Priming with sex steroids in stimulation tests for the diagnosis of GHD is still under debate. Most of the data on utility of priming during GH stimulation so far seem to support its use in the diagnosis of GHD in childhood. There is a propensity to treat growth retarded children who test subnormally to stimulation tests with GH. However, some studies analyzing the final height or height gain during GH treatment in such children failed to show any improvement in height. This paper summarizes previous studies on priming to analyze the utility of priming as a valid method to better the diagnostic capacity of the test.

Keywords: final height; growth hormone; growth hormone deficiency; growth hormone stimulation tests; priming; sex steroids

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