Jump to ContentJump to Main Navigation
Show Summary Details

Journal of Pediatric Endocrinology and Metabolism

Editor-in-Chief: Kiess, Wieland

Ed. by Bereket, Abdullah / Cohen, Pinhas / Darendeliler, Feyza / Dattani, Mehul / Gustafsson, Jan / Luo, Feihong / Mericq, Veronica / Roth, Christian / Toppari, Jorma

Editorial Board Member: Battelino, Tadej / Buyukgebiz, Atilla / Cassorla, Fernando / Chrousos, George P. / Cutfield, Wayne / Fideleff, Hugo L. / Hershkovitz, Eli / Hiort, Olaf / LaFranchi, Stephen H. / Lanes M. D., Roberto / Mohn, Angelika / Root, Allen W. / Rosenfeld, Ron G. / Werther, George / Zadik, Zvi


IMPACT FACTOR 2015: 0.912

SCImago Journal Rank (SJR) 2015: 0.493
Source Normalized Impact per Paper (SNIP) 2015: 0.600
Impact per Publication (IPP) 2015: 0.955

149,00 € / $224.00 / £112.00*

Online
ISSN
2191-0251
See all formats and pricing

 


Select Volume and Issue
Loading journal volume and issue information...

30,00 € / $42.00 / £23.00

Get Access to Full Text

Carotid arterial stiffness in overweight and obese Indian children

Deepa Pandit1 / Arun Kinare2 / Shashi Chiplonkar2 / 2 / Vaman Khadilkar2

1Agharkar Research Institute, Agarakar Road, Pune, India

2Hirabai Cowasji Jehangir Medical Research Institute, 32 Sassoon Road, Pune, India

Corresponding author: Dr. Anuradha Khadilkar, Hirabai Cowasji Jehangir Medical Research Institute, 32 Sassoon Road, Pune 411 001, India

Citation Information: Journal of Pediatric Endocrinology and Metabolism. Volume 24, Issue 1-2, Pages 97–102, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: 10.1515/jpem.2011.086, March 2011

Publication History

Published Online:
2011-03-16

Abstract

Objective: The aim of the study was to evaluate carotid arterial stiffness and intima media thickness (IMT) in obese children in comparison with healthy children, and to examine associations of lipid profile and blood pressure with carotid artery morphology.

Methods: Anthropometric and blood parameters were assessed in 44 overweight, 95 obese (6–17  years) and 69 healthy age-matched normal children. Percent body fat was measured by dual-energy X-ray absorptiometry and stiffness and IMT of the common carotid artery were evaluated using Aloka α 10 equipment.

Results: Anthropometric and lipid parameters were significantly higher in overweight and obese than in normal children (p<0.05). Stiffness (β), pulse wave velocity (PWV), elastic modulus (Ep) and blood pressure were significantly higher in obese and overweight children than in normal children (p<0.05). However, overweight and obese children did not show any significant difference in IMT compared with normal children (p>0.1). Significant positive correlation of PWV, β and Ep and negative correlation of arterial compliance with body fat and triglyceride was noted (p<0.05). Different multinomial regression models for each e-Tracking parameter indicated that the relative risk of hypertension was highest with high PWV, followed by LDL cholesterol, Ep and body fat.

Conclusion: PWV may be considered an important marker for evaluation of early functional changes of the carotid artery in children and adolescents.

Keywords: children; lipids; Indian; obesity; pulse wave velocity; stiffness

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

[1]
Min Hae Park, Áine Skow, Sara De Matteis, Anthony S. Kessel, Sonia Saxena, Russell M. Viner, and Sanjay Kinra
BMC Pediatrics, 2015, Volume 15, Number 1
[2]
Heidi Weberruß, Raphael Pirzer, Birgit Böhm, Julia Elmenhorst, Robert Dalla Pozza, Heinrich Netz, and Renate Oberhoffer
Atherosclerosis, 2015, Volume 242, Number 1, Page 48
[3]
Bülent Hacıhamdioğlu, Gönül Öçal, Merih Berberoğlu, Zeynep Şıklar, Suat Fitöz, Ercan Tutar, Gökhan Nergisoğlu, Şenay Savaş Erdeve, and Emine Çamtosun
Ultrasound in Medicine & Biology, 2014, Volume 40, Number 5, Page 871
[4]
Julio Oscar Cabrera-Rego, Gianluca Iacobellis, José Arcides Castillo-Herrera, Juan Valiente-Mustelier, Julio C. Gandarilla-Sarmientos, Silvia María Marín-Juliá, and Juliette Navarrete-Cabrera
Pediatric Cardiology, 2014, Volume 35, Number 3, Page 450
[5]
A V Khadilkar, N J Sanwalka, S A Chiplonkar, V V Khadilkar, and D Pandit
International Journal of Obesity, 2013, Volume 37, Number 7, Page 947
[6]
Ragab A. Mahfouz, Ashraf Dewedar, Amr Abdelmoneim, and Ekhlas M. Hossien
Echocardiography, 2012, Volume 29, Number 8, Page 984
[7]
V. V. Khadilkar, Anuradha V. Khadilkar, A. B. Borade, and S. A. Chiplonkar
Indian Pediatrics, 2012, Volume 49, Number 1, Page 29
[8]
D Pandit, S Chiplonkar, A Khadilkar, A Kinare, and V Khadilkar
International Journal of Obesity, 2011, Volume 35, Number 10, Page 1318

Comments (0)

Please log in or register to comment.