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Abstract
Maternal adrenal cortical carcinoma in pregnancy is rare. We report a case of an infant born to a mother with a history of adrenal cortical carcinoma. The pregnancy was complicated by fetal exposure to mitotane and dexamethasone. Despite the potential teratogenic exposures, there was no evidence of adrenal dysfunction in the infant. Growth and development at 12 months of age are normal and prognosis appears favorable. The long-term impact of fetal exposure to mitotane and glucocorticoid requires further investigation.
Keywords: adrenal cortical carcinoma; adrenal function; dexamethasone; fetus; mitotane; newborn; pregnancy
Published Online: 2011-04-01
Published in Print: 2011-04-01
©2011 by Walter de Gruyter Berlin New York