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Journal of Pediatric Endocrinology and Metabolism

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Ganglioneuroblastoma in a young child with Turner syndrome

1 / David F. Crudo2

1Department of Pediatrics, Tripler Army Medical Center, Honolulu, HI, USA

2Department of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, NC, USA

Corresponding author: Jordan E. Pinsker, MD, Chief, Division of Pediatric Endocrinology, Department of Pediatrics, Tripler Army Medical Center, Mail Code MCHK-PE, 1 Jarrett White Road, Honolulu, HI 96859-5000, USA

Citation Information: Journal of Pediatric Endocrinology and Metabolism. Volume 25, Issue 7-8, Pages 799–800, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: 10.1515/jpem-2012-0102, July 2012

Publication History

Received:
2012-05-23
Accepted:
2012-06-23
Published Online:
2012-07-21

Abstract

X chromosome aneuploidy has been identified as a potential risk factor for the development of neuroblastic tumors. We report a case of a 4-year-old girl with a 45,X karyotype incidentally discovered to have a large ganglioneuroblastoma on initial screening ultrasound. The incidence of these tumors in girls with Turner syndrome as well as their possible relationship to recombinant human growth hormone treatment is discussed.

Keywords: abdominal mass; ganglioneuroblastoma; neuroblastoma; Turner syndrome

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