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Journal of Pediatric Endocrinology and Metabolism

Editor-in-Chief: Kiess, Wieland

Editorial Board Member: Darendeliler, Feyza / Gustafsson, Jan / Luo, Feihong / Mericq, Veronica / Lanes M. D., Roberto / Battelino, Tadej / Buyukgebiz, Atilla / Cassorla, Fernando / Chrousos, George P. / Cutfield, Wayne / Fideleff, Hugo L. / Hershkovitz, Eli / LaFranchi, Stephen H. / Mohn, Angelika / Root, Allen W. / Rosenfeld, Ron G. / Wabitsch, Martin / Werther, George / Zadik, Zvi

12 Issues per year

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Metabolic alterations in pregnant women: gestational diabetes

Daniela Oliveira1 / Joana Pereira1 / 1, 2

1Department of Chemical and Biomolecular Sciences and Unit of Molecular Mechanisms of Disease from the Centre of Environmental and Health Research, School of Allied Health Sciences, Porto Polytechnic, Porto, Portugal

2Faculty of Medicine, Department of Biomedical Engineering, School of Management and Industrial Studies, Porto Polytechnic and Centre of Pharmacology and Chemical Biopathology (U38-FCT), Porto University, Porto, Portugal

Corresponding author: Prof. Rúben Fernandes, Department of Chemical and Biomolecular Sciences and Unit of Molecular Mechanisms of Disease from the Centre of Environmental and Health Research, School of Allied Health Sciences, Porto Polytechnic, Rua Valente Perfeito, 322 Vila Nova de Gaia, Porto 4400-330, Portugal

Citation Information: Journal of Pediatric Endocrinology and Metabolism. Volume 25, Issue 9-10, Pages 835–842, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: 10.1515/jpem-2012-0175, September 2012

Publication History

Received:
2012-06-07
Accepted:
2012-08-05
Published Online:
2012-09-06

Abstract

Gestational diabetes mellitus (GDM) and controversy are old friends. The impact of GDM on maternal and fetal health has been increasingly recognized. Nevertheless, universal consensus on the diagnostic methods and thresholds has long been lacking. Published guidelines from major societies differ significantly from one another, with recommendations ranging from aggressive screening to no routine screening at all. As a result, real-world practice is equally varied. This article recaps the latest evidence-based recommendations for the diagnosis and classification of GDM. It reviews the current evidence base for intensive multidisciplinary treatment of GDM and provides recommendations for postpartum management to delay and/or prevent progression to type 2 diabetes.

Keywords: diagnosis; gestational diabetes; metabolic alterations; treatment

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