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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Greenough, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Chappelle, Joseph / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / D'Alton, MD, Mary E. / Dimitrou, G. / Grunebaum, Amos / Hentschel, Roland / Köpcke, W. / Kawabata, Ichiro / Keirse, M.J.M.C. / Kurjak M.D., Asim / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Makatsariya, Alexander / Nishida, Hiroshi / Papp, Zoltán / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Seri, MD, PhD, HonD, Istvan / Vetter, Klaus / Winn, MD, Hung N. / Young, Bruce K. / Zimmermann, Roland

6 Issues per year

Increased IMPACT FACTOR 2012: 1.949
Rank 29 out of 77 in category Obstretics & Gynecology and 39 out of 121 in category Pediatrics in the 2012 Thomson Reuters Journal Citation Report/Science Edition

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The potential role of high or low birthweight as risk factor for adult schizophrenia

Giuseppe Bersani1 / Giorgiana Manuali2 / Luisa Ramieri3 / Ines Taddei4 / Iliana Bersani5 / Filippo Conforti6 / Maria Sofia Cattaruzza7 / John Osborn8 / Paolo Pancheri9

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Corresponding author: Prof. Giuseppe Bersani III Psychiatric Clinic, Department of Psychiatric Sciences and Psychological Medicine Special Service of Psychopharmacology and Psychosomatic Medicine University of Rome “La Sapienza” Viale dell'Università 30, 00185 Rome, Italy Tel.: +39-0649914591 Fax: +39-064454765

Citation Information: Journal of Perinatal Medicine. Volume 35, Issue 2, Pages 159–161, ISSN (Online) 1619-3997, ISSN (Print) 0300-5577, DOI: 10.1515/JPM.2007.021, March 2007

Publication History

Received:
May 9, 2006
Revised:
September 8, 2006
Accepted:
December 11, 2006
Published Online:
2007-03-07

Abstract

Objective: Obstetric complications may be an important factor in the development of schizophrenia. The aim of this study is to evaluate the role of these complications in the development of schizophrenia in adult life, with particular attention to the potential role of birth weight.

Method: We carried out a case-control study, comprising schizophrenics and patients with diseases of the schizophrenia spectrum as cases, and their healthy male brothers as controls. Obstetric complications were assessed using the “Midwife Protocol” of Parnas et al.

Results: The main result was that birth weight may be a risk factor for schizophrenia, as indicated by odds ratio analysis. The confidence intervals are very wide and, without compromising the clinical significance of the results, they give a limited indication of the real entity of the risk.

Conclusions: The results contribute to understanding of the role played by a single complications.

Keywords: Birth weight; fetal growth; obstetric complications; pregnancy; shizophrenia

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