Jump to ContentJump to Main Navigation

Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Greenough, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Chappelle, Joseph / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / D'Alton, MD, Mary E. / Dimitrou, G. / Grunebaum, Amos / Hentschel, Roland / Köpcke, W. / Kawabata, Ichiro / Keirse, M.J.M.C. / Kurjak M.D., Asim / Lee, Ben H. / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Makatsariya, Alexander / Nishida, Hiroshi / Papp, Zoltán / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Romero, Roberto / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Seri, Istvan / Vetter, Klaus / Winn, Hung N. / Young, Bruce K. / Zimmermann, Roland

6 Issues per year


IMPACT FACTOR 2013: 1.425

SCImago Journal Rank (SJR): 0.782
Source Normalized Impact per Paper (SNIP): 0.928

VolumeIssuePage

Issues

Obstetrical factors for death and brain injury among extremely-low-birth-weight infants

Tatsuya Fukami1 / Toshiyuki Yoshizato2 / Toshiko Mori3 / Ko Yukitake4 / Yoshihiro Miyake5 / Tatsuhiko Kawarabayashi6

1Department of Obstetrics and Gynecology, School of Medicine, Fukuoka University, Fukuoka, Japan

2Center for Maternal, Fetal and Neonatal Medicine, Fukuoka University Hospital, Fukuoka, Japan

3Center for Maternal, Fetal and Neonatal Medicine, Fukuoka University Hospital, Fukuoka, Japan

4Center for Maternal, Fetal and Neonatal Medicine, Fukuoka University Hospital, Fukuoka, Japan

5Department of Public Health, School of Medicine, Fukuoka University, Fukuoka, Japan

6Department of Obstetrics and Gynecology, School of Medicine, Fukuoka University, Fukuoka, Japan

Corresponding author: Toshiyuki Yoshizato, MD, PhD Assistant professor Center for Maternal, Fetal and Neonatal Medicine Fukuoka University Hospital 7-45-1 Nanakuma Jonan-ku Fukuoka 814-0180 Japan Tel.: +81-92-801-1011 ext.3505 Fax: +81-92-865-4114

Citation Information: Journal of Perinatal Medicine. Volume 35, Issue 6, Pages 543–549, ISSN (Online) 16193997, ISSN (Print) 03005577, DOI: 10.1515/JPM.2007.111, December 2007

Publication History

Received:
2006-09-14
Revised:
2007-07-09
Accepted:
2007-09-20
Published Online:
2007-12-05

Abstract

Objective: To examine the obstetrical risk factors for death and brain injury among extremely-low-birth-weight (ELBW) infants (birth weight <1000 g).

Study design: Study subjects were 121 ELBW infants born at a single tertiary perinatal center. Death among ELBW infants was considered to have occurred when subjects died within their corrected age of 40 weeks. In the sub-analysis of the 91 ELBW infants who survived their corrected age of 40 weeks, brain injury was defined as present when criteria based on ultrasound and/or MRI were substantiated.

Results: A birth weight of <800 g [adjusted odds ratio (OR), 14.57; 95% confidence interval (CI), 4.72–56.98], a younger gestational age of <26 weeks (adjusted OR, 4.64; 95% CI, 1.60–14.90), and a low Apgar score of <5 (adjusted OR, 3.88; 95% CI, 1.32–12.45) were significantly associated with death among ELBW infants. A maternal age of 30 years or older (adjusted OR, 3.71; 95% CI, 1.19–13.35) was only associated with brain injury among surviving ELBW infants.

Conclusion: Obstetrical care should be aimed at preventing or predicting premature delivery especially at <26 weeks of gestation.

Keywords: Brain injury; extremely-low-birth-weight infants; obstetrical risk factors

Comments (0)

Please log in or register to comment.