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Publication Date:
January 2010
ISSN:
1619-3997
DOI:
10.1515/jpm.2010.010

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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Greenough, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Aslam, Muhammad / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Brezinka, Christoph / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / Dimitrou, G. / Foulon, Walter / Grunebaum, G. E. / Harding, Jane / Hentschel, Roland / Kawabata, Ichiro / Keirse, M.J.M.C. / Kurjak M.D., Asim / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Nishida, Hiroshi / Papp, Zoltán / Makatsariya, Alexander / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Geijn, Herman P. / Vetter, Klaus / Young, Bruce K. / Zimmermann, Roland / Köpcke, W.

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Atosiban vs. ritodrine as a tocolytic in external cephalic version at term: a prospective cohort study

Jorge Burgos1 / Nekane Eguiguren1 / Eider Quintana1 / Patricia Cobos1 / Maria del Mar Centeno1 / Rosa Larrieta1 / Luis Fernández-Llebrez1

1Department of Obstetrics and Gynecology, Cruces University Hospital, Baracaldo, Vizcaya, Spain

Corresponding author: Jorge Burgos San Cristóbal, MD Departamento Obstetricia y Ginecología Hospital de Cruces C/Plaza de Cruces sn 48903 Baracaldo Vizcaya Spain

Citation Information: Journal of Perinatal Medicine. Volume 38, Issue 1, Pages 23–28, ISSN (Online) 1619-3997, ISSN (Print) 0300-5577, DOI: 10.1515/jpm.2010.010, January 2010

Publication History:
Received:
2009-05-03
Revised:
2009-06-04
Accepted:
2009-08-03
Published Online:
2010-01-05

Abstract

Objective: To compare the success rate of external cephalic version (ECV) at term using ritodrine or atosiban as a tocolytic agent.

Study design: Prospective cohort study with a sample of 236 pregnant women with a breech presentation at term, from November 2006 to March 2008. Data have been analyzed from the moment the cephalic version is performed until the time of delivery.

Results: ECV success rate using ritodrine as a tocolytic agent was 56.8% compared to 31.4% with atosiban. Ritodrine increases the version success potential more significantly than atosiban (P<0.05). In both cases, the use of ECV reduced the rate of cesarean sections, although a higher number of versions are required with atosiban [numbers needed to treat (NNT)=9.08] to avoid a cesarean section compared to ritodrine (NNT=3.41).

Conclusions: Ritodrine seems better than atosiban as tocolytic agent for ECVs.

Keywords: Breech presentation; external cephalic version (ECV); ritodrine; tocolityc agents; vasotocin

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