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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Greenough, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Chappelle, Joseph / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / D'Alton, MD, Mary E. / Dimitrou, G. / Grunebaum, Amos / Hentschel, Roland / Köpcke, W. / Kawabata, Ichiro / Keirse, M.J.M.C. / Kurjak M.D., Asim / Lee, MD MPH MSCR, Ben H. / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Makatsariya, Alexander / Nishida, Hiroshi / Papp, Zoltán / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Romero, Roberto / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Seri, Istvan / Vetter, Klaus / Winn, Hung N. / Young, Bruce K. / Zimmermann, Roland

7 Issues per year

IMPACT FACTOR 2013: 1.425

SCImago Journal Rank (SJR): 0.782
Source Normalized Impact per Paper (SNIP): 0.928



Oxytocin versus dinoprostone vaginal insert for induction of labor after previous cesarean section: a retrospective comparative study

1, 2 / Jorge Burgos1, 2 / Patricia Cobos1, 2 / Juan Carlos Melchor1, 2 / Carmen Osuna1, 2 / Maria del Mar Centeno1, 2 / Rosa Larrieta1, 2 / Luis Fernández-Llebrez1, 2 / Txantón Martínez-Astorquiza1, 2

1Department of Obstetrics and Gynecology, Cruces University Hospital, Biscay, Spain

2Faculty of Medicine, University of the Basque Country, Biscay, Spain

Corresponding author: Leire Rodríguez Gómez Servicio de Obstetricia y Ginecología Hospital Universitario de Cruces Plaza de Cruces SN 48903 Baracaldo Vizcaya Spain Tel.: +946006000

Citation Information: Journal of Perinatal Medicine. Volume 39, Issue 4, Pages 397–402, ISSN (Online) 1619-3997, ISSN (Print) 0300-5577, DOI: 10.1515/jpm.2011.030, May 2011

Publication History

Published Online:


Objective: To compare the efficacy and safety of two methods for induction of labor after previous cesarean section.

Methods: To compare 247 women with a previous cesarean section who were induced with a dinoprostone vaginal insert and 279 women with a previous cesarean section induced with oxytocin, between 2001 and 2008. We evaluated vaginal delivery rate, maternal morbidity and newborn morbidity and mortality.

Results: The overall rate of vaginal delivery was 65.2%. We did not find significant differences between induction with dinoprostone vaginal insert and oxytocin in the rate of cesarean section performed (35.6% vs. 34.1%, P=0.71). There were nine cases of uterine rupture (rate of 1.7%), of which four occurred with dinoprostone vaginal insert and five when using oxytocin (P=0.89). We found no significant differences in neonatal outcomes.

Conclusions: Both tested methods appear to be equally safe and effective for induction of labor in women with a previous cesarean section.

Keywords: Cesarean section; dinoprostone; induced; labor; obstetric labor complications; oxytocics; trial of labor; uterine rupture; vaginal birth after cesarean

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