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Publication Date:
September 2011
ISSN:
1619-3997
DOI:
10.1515/jpm.2011.054

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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Greenough, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Aslam, Muhammad / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Brezinka, Christoph / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / Dimitrou, G. / Foulon, Walter / Grunebaum, G. E. / Harding, Jane / Hentschel, Roland / Kawabata, Ichiro / Keirse, M.J.M.C. / Kurjak M.D., Asim / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Nishida, Hiroshi / Papp, Zoltán / Makatsariya, Alexander / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Geijn, Herman P. / Vetter, Klaus / Young, Bruce K. / Zimmermann, Roland / Köpcke, W.

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Inter- and intra-observer variation of fetal volume measurements with three-dimensional ultrasound in the first trimester of pregnancy

1 / Joost van de Ven2 / S. Guid Oei2, 3

1Department of Gynecology and Obstetrics, Atrium Medical Center, Parkstad, The Netherlands

2Department of Gynecology and Obstetrics, Màxima Medical Center, Eindhoven-Veldhoven, The Netherlands

3Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands

Corresponding author: Nicol A.C. Smeets Atrium Medical Center, Parkstad Henri Dunantstraat 5, 6401 CX Heerlen, The Netherlands Tel.: +31 45 57 66 51 3 Fax: +31 45 57 66 62 5

Citation Information: Journal of Perinatal Medicine. Volume 39, Issue 5, Pages 539–543, ISSN (Online) 1619-3997, ISSN (Print) 0300-5577, DOI: 10.1515/jpm.2011.054, September 2011

Publication History:
Received:
2010-10-19
Revised:
2011-02-26
Accepted:
2011-03-15
Published Online:
2011-09-06

Abstract

Objectives: To determine the inter- and intra-observer variation of volume calculations of human fetuses at a gestational age of 11+0–13+6 weeks by three-dimensional ultrasound (3DUS).

Methods: 3DUS datasets were acquired during nuchal translucency measurements. The fetal volume (FV) was measured in 65 cases by two independent investigators. The Virtual Organ Computer aided AnaLysis (VOCAL™) imaging software was used to manually calculate the FV (rotational angle 9°). Inter- and intra-observer variation were assessed by Bland-Altman plots and intraclass correlation coefficients (ICC).

Results: Both inter- and intraobserver reproducibility were highly reliable as shown by the Bland-Altman plots and an ICC of respectively 0.934 and 0.994.

Conclusion: FV calculation by 3DUS with VOCAL and a rotational angle of 9° is feasible and has a high inter- and intraobserver reliability in the first trimester of pregnancy.

Keywords: Fetal volume; first trimester; interobserver variation; intraobserver variation; three-dimensional ultrasound

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