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Publication Date:
February 2012
ISSN:
1619-3997
DOI:
10.1515/jpm.2011.139

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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Greenough, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Aslam, Muhammad / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Brezinka, Christoph / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / Dimitrou, G. / Foulon, Walter / Grunebaum, G. E. / Harding, Jane / Hentschel, Roland / Kawabata, Ichiro / Keirse, M.J.M.C. / Kurjak M.D., Asim / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Nishida, Hiroshi / Papp, Zoltán / Makatsariya, Alexander / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Geijn, Herman P. / Vetter, Klaus / Young, Bruce K. / Zimmermann, Roland / Köpcke, W.

6 Issues per year

IMPACT FACTOR 2011: 1.702
5-year IMPACT FACTOR: 1.779
Rank 36 out of 79 in category Obstretics and Gynecology and 45 out of 113 in category Pediatrics in the 2011 Thomson Reuters Journal Citation Report/Science Edition

VolumeIssuePage

Issues

Fetal magnetocardiography (fMCG): moving forward in the establishment of clinical reference data by advanced biomagnetic instrumentation and analysis

Isabelle Kiefer-Schmidt1, 2 / Minha Lim1, 2 / Annette Wacker-Gußmann2, 4 / Eric Ortiz2 / Harald Abele1 / Karl Oliver Kagan1 / Renate Kaulitz3 / 1 / Hubert Preissl2, 5

1Department of Obstetrics and Gynecology, University Hospital, Tübingen, Germany

2MEG and fMEG Center, University of Tübingen, Tübingen, Germany

3Department of Pediatric Cardiology, University Children’s Hospital, Tübingen, Germany

4Department of Pediatrics Neonatology, University Hospital, Tübingen, Germany

5Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock, AR, USA

Corresponding author: Prof. Diethlem Wallwiener Department of Obstetrics and Gynecology University Hospital of Tübingen Calwerstr. 7 D-72076 Tübingen Germany Tel.: +49 7071 2982246 Fax: +49 7071 292202

Citation Information: Journal of Perinatal Medicine. Volume 40, Issue 3, Pages 277–286, ISSN (Online) 1619-3997, ISSN (Print) 0300-5577, DOI: 10.1515/jpm.2011.139, February 2012

Publication History:
Received:
2011-06-15
Revised:
2011-11-25
Accepted:
2011-11-28
Published Online:
2012-02-10

Abstract

Cardiotocography and echocardiography are currently standard for fetal heart monitoring. However, both do not provide adequate temporal resolution to measure fetal cardiac time intervals and detect arrhythmias, which can occur during normal sinus rhythm. Fetal magnetocardiography (fMCG) is a non-invasive technique measuring magnetic signals generated by fetal heart activity. Most fMCG devices are installed in research institutions limiting the implementation of this method in a clinical setting. Several institutions made a step forward by installing devices, in particular for fetal investigations, in hospital sites to evaluate the clinical benefit. Based on instrumentation differences which can affect signal quality, there is still no established reference database for fetal cardiac time intervals. A new magnetograph dedicated to fetal recordings was implemented with improved patient comfort. The setting was optimized to establish a standard. A total of 103 healthy fetuses starting as early as possible after the first trimester were recorded and fMCG values of cardiac time intervals were compared to former studies. Data allowed high and reliable detection for all fMCG components starting at 17 weeks. The data were comparable to fMCG multicenter studies, fetal electrocardiography and neonatal ECG results and could serve as a database of norm values for further investigation of fetal arrhythmias.

Keywords: Biosignal processing; fetal cardiac time intervals (fCTIs); fetal magnetocardiography (fMCG)

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