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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Greenough, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Chappelle, Joseph / Aslam, Muhammad / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / Dimitrou, G. / Grunebaum, G. E. / Harding, Jane / Hentschel, Roland / Kawabata, Ichiro / Keirse, M.J.M.C. / Kurjak M.D., Asim / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Makatsariya, Alexander / Nishida, Hiroshi / Papp, Zoltán / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Geijn, Herman P. / Vetter, Klaus / Young, Bruce K. / Zimmermann, Roland / Köpcke, W.

6 Issues per year

Increased IMPACT FACTOR 2012: 1.949
Rank 29 out of 77 in category Obstretics & Gynecology and 39 out of 121 in category Pediatrics in the 2012 Thomson Reuters Journal Citation Report/Science Edition



Diet or medically treated gestational diabetes: is there any difference for obstetrical and neonatal complications? A French cohort study

Audrey Blachier1 / Corinne Alberti2–4, , / Diane Korb5, 6 / Thomas Schmitz5, 6 / Vexiau Patrick7 / Boissinot Christine6 / Jean-François Oury5, 6 / 6

1Département d’information médicale, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, 48 Boulevard Sérurier, 75019, Paris, France

2Unité d’épidémiologie clinique, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris and Université Paris 7 Denis Diderot, 48 Boulevard Sérurier, 75019, Paris, France

3Université Paris Diderot, Sorbonne Paris Cité, Unité d’Épidémiologie Clinique, Paris, France

4INSERM, CIE 5, Paris, France

5Université Paris 7 Denis Diderot, UFR de Médecine, Paris, France

6Service de gynécologie-obstétrique, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, 48 Boulevard Sérurier, 75019, Paris, France

7Service d’endocrinologie et de diabétologie, Hôpital Saint Louis, Assistance Publique-Hôpitaux de Paris, 1 avenue Claude-Vellefaux, 75010, Paris, France

Corresponding author: Pr. Olivier Sibony, Service de gynécologie-obstétrique, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, 48 Boulevard Sérurier, 75019 Paris, France, Tel.: +33 1 40 03 24 54, Fax: +33 1 40 03 53 76, E-mail:

Citation Information: Journal of Perinatal Medicine. Volume 0, Issue 0, Pages 1–5, ISSN (Online) 1619-3997, ISSN (Print) 0300-5577, DOI: 10.1515/jpm-2013-0079, November 2013

Publication History:
Published Online:


Objective: The aim of the present study was to determine specific obstetrical and neonatal complications associated with diet-treated gestational diabetes (DTGD) and medically treated gestational diabetes (MTGD).

Methods: This is a prospective cohort study of women followed in the Robert Debré Hospital (France, Paris) and who have given birth between 1 January, 2004, and 19 November, 2010. Clinical, biological, maternal and neonatal data were reported in the maternity database. Associations between obstetrical and neonatal complications and gestational diabetes were evaluated by estimating odd ratios (ORs) and their 95% CIs, using a logistic regression model.

Results: 16,244 pregnancies were included in the study. 1515 (9.3%) women had gestational diabetes: 1108 (7.3%) had DTGD, 243 (1.7%) had MTGD. After full adjustment, MTGD was associated with an increased risk of nonscheduled cesarean (ORnonscheduled=2.3; 95% CI: 1.6–3.3; P<0.001) while DTGD was not (ORnonscheduled=1.0; 95% CI: 0.8–1.3; P<0.96). Clinical macrosomia was positively associated with DTGD (OR=2; 95% CI: 1.7–2.4; P<0.0001) or MTGD (OR=2.9; 95% CI: 2.1–3.9; P<0.0001).

Conclusion: This study confirms that macrosomia is the main complication of DTGD. By contrast, DTGD was not associated with neonatal hypoglycemia and cesarean, while these complications were associated with MTGD.

Keywords: Complications; gestational diabete; diet

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