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LaboratoriumsMedizin

Editor-in-Chief: Schimke, Ingolf

Editorial Board Member: Bidlingmaier, Martin / Karsten, Conrad / Fraunberger, Peter / Kiehntopf, Michael / Klein, Hanns-Georg / Klouche, Mariam / Kohse, Klaus P. / Kratzsch, Jürgen / Luppa, Peter B. / März, Winfried / Nebe, Carl Thomas / Orth, Matthias / Ruf, Andreas / Schuff-Werner, Peter / Steimer, Werner / Stieber, Petra / Weber, Bernard / Wieland, Eberhard / Sack, Ulrich / Tumani, Hayrettin / Zettl, Uwe K.

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Immunotherapy and vaccination: interfering factors in serological diagnostics1

Claudia Reinheimer1 / Hans W. Doerr1

1Institut für Medizinische Virologie, Johann Wolfgang von Goethe-Universität Frankfurt/Main, Frankfurt a.M., Germany

Correspondence: Claudia Reinheimer, Institut für Medizinische Virologie, Johann Wolfgang von Goethe-Universität Frankfurt/Main, Paul-Ehrlich-Straße 40, 60596 Frankfurt a.M., Germany Tel.: +49 69/6301-83062 Fax: +49 69/6301-83061

Citation Information: LaboratoriumsMedizin. Volume 34, Issue 5, Pages -–-, ISSN (Online) 1439-0477, ISSN (Print) 0342-3026, DOI: 10.1515/JLM.2010.045et, December 2010

Publication History

Published Online:
2010-12-16

Abstract

A variety of factors are known to influence qualitative and quantitative serological assays. Here, we discuss such pitfalls in serology emerging in a case of influenza A/H1N1v-hemagglutination inhibition test (H1N1-HHT) subsequent to hyposensitization and vaccinations. Assuming that hyposensitization and vaccinations are frequently provided services, their potential interference with serological assays should be considered.

Keywords: disturbing factors in serodiagnosis; H1N1; hyposensitization; vaccination

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