New Journal in 2012!
Editor-in-Chief: Kumar, Challa
Editorial Board Member: Hamblin, Michael R. / Drikakis, Dimitris / Bianco, Alberto / Jin, Rongchao / Jelinek, Raz / Voelcker, Nicolas / Köhler, J. Michael / Hudait, Mantu K. / Dai, Ning / Baba, Yoshinobu / Bryan, Lynn A. / Thiessen, Rose / Alexiou, Christoph
6 Issues per year
Volume 2 (2013)
Most Downloaded Articles
- The impacts of nanotechnology on catalysis by precious metal nanoparticles by Jin, Rongchao
- Can nanotechnology potentiate photodynamic therapy? by Huang, Ying-Ying/ Sharma, Sulbha K./ Dai, Tianhong/ Chung, Hoon/ Yaroslavsky, Anastasia/ Garcia-Diaz, Maria/ Chang, Julie/ Chiang, Long Y. and Hamblin, Michael R.
- Interactions of graphene and graphene oxide with proteins and peptides by Zhang, Yan/ Wu, Congyu/ Guo, Shouwu and Zhang, Jingyan
- Surfactant-free solution-based synthesis of metallic nanoparticles toward efficient use of the nanoparticles’ surfaces and their application in catalysis and chemo-/biosensing by Kawasaki, Hideya
- Carbon nanotubes: a promise for nerve tissue engineering? by Bosi, Susanna/ Fabbro, Alessandra/ Ballerini, Laura and Prato, Maurizio
Multifunctionalized carbon nanotubes as advanced multimodal nanomaterials for biomedical applications
1CNRS, Institut de Biologie Moléculaire et Cellulaire, Laboratoire d’Immunologie et Chimie Thérapeutiques, 15 Rue René Descartes, 67084 Strasbourg, France
Citation Information: Nanotechnology Reviews. Volume 1, Issue 1, Pages 17–29, ISSN (Online) 2191-9097, ISSN (Print) 2191-9089, DOI: 10.1515/ntrev-2011-0002, January 2012
The increasing importance of nanotechnology in the field of biomedical applications has encouraged the development of new nanomaterials endowed with multiple functions. Novel nanoscale drug delivery systems with diagnostic, imaging and therapeutic properties hold many promises for the treatment of different types of diseases, including cancer, infection and neurodegenerative syndromes. Functionalized carbon nanotubes (CNTs) are one of the most recent type of nanomaterial developed in biomedicine as they can be designed and imparted with multimodal capabilities. Indeed, the possibility of inserting different functionalities on CNTs is opening the possibility to exploit them on new strategies that combine diagnosis with improved therapeutic efficacies. In this review, we describe the different approaches that have been recently developed to generate multifunctionalized CNTs for biomedical applications. In particular, covalent and non-covalent double and triple functionalization methods are discussed, putting in evidence their use in vitro and in vivo and highlighting the advantages and the drawbacks of these new systems. Preclinical studies have demonstrated that multifunctional CNTs are highly promising when combining diagnostic, imaging and therapeutic modalities.