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Polish Journal of Chemical Technology

The Journal of West Pomeranian University of Technology, Szczecin

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Kinetics and mechanism of meso-tetraphenylporphyriniron(III) chloride (TPP) catalysed oxidation of indole by sodium perborate

D. Kungumathilagam1 / 1

1Department of Chemistry, Sona College of Technology, Salem-636 005, India

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Citation Information: Polish Journal of Chemical Technology. Volume 15, Issue 2, Pages 107–111, ISSN (Online) 1899-4741, ISSN (Print) 1509-8117, DOI: 10.2478/pjct-2013-0031, July 2013

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Developing catalyst is very significant for biologically important reactions which yield products, used as drugs. Mechanistic study on meso-tetraphenylporphyriniron(III) chloride (TPP) catalysed oxidation of indole by sodium perborate in aqueous acetic acid medium have been carried out. The reaction follows a fractional order with respect to substrate and catalyst. The order with respect to oxidant was found to be one. Increase in the percentage of acetic acid and increase in the concentration of [H+] decreased the rate. The reaction fails to initiate polymerization, and a radical mechanism is ruled out. Activation and thermodynamic parameters have been computed. A suitable kinetic scheme based on these observations has been proposed. Significant catalytic activity is observed for the reaction system in the presence of TPP.

Keywords : indole; sodium perborate; meso-tetraphenylporphyriniron(III) chloride; oxidation

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