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Reviews in Analytical Chemistry

Editor-in-Chief: Schechter, Israel

Editorial Board Member: Pauw, Edwin / Vries, Mattanjah / Grushka, Eli / Laserna, J. / Licht, Stuart / Lubman, David / Mandler, Daniel / Palleschi, Vincenzo / Sigman, Michael / Whitesides, George / Yarnitzki, Chaim

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On-chip redox cycling techniques for electrochemical detection

Enno Kätelhön1, 2 / 1, 2

1Institute of Bioelectronics (ICS-8/PGI-8), Forschungszentrum Jülich GmbH, 52425 Jülich, Germany

2JARA, Fundamentals of Future Information Technology, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany

Corresponding author

Citation Information: Reviews in Analytical Chemistry. Volume 31, Issue 1, Pages 7–14, ISSN (Online) 2191-0189, ISSN (Print) 0793-0135, DOI: 10.1515/revac-2011-0031, February 2012

Publication History

Published Online:


During the last two decades, redox cycling techniques have evolved as a promising technique for the electrochemical detection of molecules that can undergo subsequent redox reactions. In particular, chip-based techniques received growing attention due to the option of parallel fabrication and easy integration into lab-on-a-chip devices. In here, we provide a review on current implementations of on-chip redox cycling sensors. Advantages and limitations of various approaches are discussed with regard to their fabrication process and performance.

Keywords: electrochemical sensors; interdigitated arrays; nanocavity sensors; nanofluidic sensors; redox cycling

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