Neuroimaging for drug addiction and related behaviors : Reviews in the Neurosciences uses cookies, tags, and tracking settings to store information that help give you the very best browsing experience.
To understand more about cookies, tags, and tracking, see our Privacy Statement
I accept all cookies for the De Gruyter Online site

Jump to ContentJump to Main Navigation

Reviews in the Neurosciences

Editor-in-Chief: Huston, Joseph P.

Editorial Board Member: Topic, Bianca / Adeli, Hojjat / Buzsaki, Gyorgy / Crawley, Jacqueline / Crow, Tim / Eichenbaum, Howard / Gold, Paul / Holsboer, Florian / Korth, Carsten / Lubec, Gert / McEwen, Bruce / Pan, Weihong / Pletnikov, Mikhail / Robbins, Trevor / Schnitzler, Alfons / Stevens, Charles / Steward, Oswald / Trojanowski, John

IMPACT FACTOR increased in 2014: 3.330
5-year IMPACT FACTOR: 3.358
Rank 97 out of 252 in category Neurosciences in the 2014 Thomson Reuters Journal Citation Report/Science Edition

SCImago Journal Rank (SJR) 2014: 1.488
Source Normalized Impact per Paper (SNIP) 2014: 0.885
Impact per Publication (IPP) 2014: 3.675

Access brought to you by:

provisional account



Neuroimaging for drug addiction and related behaviors

Muhammad A. Parvaz1 / Nelly Alia-Klein1 / Patricia A. Woicik1 / Nora D. Volkow2 / 1

1Medical Department, Brookhaven National Laboratory, 30 Bell Ave., Bldg. 490, Upton, NY 11973-5000, USA

2National Institute of Drug Abuse, Bethesda, MD 20892, USA

Corresponding author

Citation Information: Reviews in the Neurosciences. Volume 22, Issue 6, Pages 609–624, ISSN (Online) 2191-0200, ISSN (Print) 0334-1763, DOI: 10.1515/RNS.2011.055, November 2011

Publication History

Published Online:


In this review, we highlight the role of neuroimaging techniques in studying the emotional and cognitive-behavioral components of the addiction syndrome by focusing on the neural substrates subserving them. The phenomenology of drug addiction can be characterized by a recurrent pattern of subjective experiences that includes drug intoxication, craving, bingeing, and withdrawal with the cycle culminating in a persistent preoccupation with obtaining, consuming, and recovering from the drug. In the past two decades, imaging studies of drug addiction have demonstrated deficits in brain circuits related to reward and impulsivity. The current review focuses on studies employing positron emission tomography (PET), functional magnetic resonance imaging (fMRI), and electroencephalography (EEG) to investigate these behaviors in drug-addicted human populations. We begin with a brief account of drug addiction followed by a technical account of each of these imaging modalities. We then discuss how these techniques have uniquely contributed to a deeper understanding of addictive behaviors.

Keywords: dopamine; electroencephalography (EEG); event-related potentials (ERPs); magnetic resonance imaging (MRI); positron emission tomography (PET); prefrontal cortex

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

Bailey W. Miller, Melissa G. Wroten, Arianne D. Sacramento, Hannah E. Silva, Christina B. Shin, Philip A. Vieira, Osnat Ben-Shahar, Tod E. Kippin, and Karen K. Szumlinski
Addiction Biology, 2016, Page n/a
Elisabeth Jonckers, Disha Shah, Julie Hamaide, Marleen Verhoye, and Annemie Van der Linden
Frontiers in Pharmacology, 2015, Volume 6
Uma Vaidyanathan, Scott I. Vrieze, and William G. Iacono
Psychological Inquiry, 2015, Volume 26, Number 3, Page 209
Jennifer Schmidt and Alexandra Martin
Applied Psychophysiology and Biofeedback, 2015
Bianca Jupp and Jeffrey W. Dalley
Neuropharmacology, 2014, Volume 76, Page 487
Olga Rass, Woo-Young Ahn, and Brian F. O’Donnell
Clinical Neurophysiology, 2015
Lucia M. Alba-Ferrara, Francisco Fernandez, Ramiro Salas, and Gabriel A. de Erausquin
Addictive Disorders & Their Treatment, 2014, Volume 13, Number 4, Page 159
Claudio Imperatori, Mariantonietta Fabbricatore, Marco Innamorati, Benedetto Farina, Maria Isabella Quintiliani, Dorian A. Lamis, Edoardo Mazzucchi, Anna Contardi, Catello Vollono, and Giacomo Della Marca
Brain Imaging and Behavior, 2014
Kathleen A. Garrison and Marc N. Potenza
Current Psychiatry Reports, 2014, Volume 16, Number 12
Helen S. Mayberg
Hastings Center Report, 2014, Volume 44, Number s2, Page S31
Femke T.A. Buisman-Pijlman, Nicole M. Sumracki, Jake J. Gordon, Philip R. Hull, C. Sue Carter, and Mattie Tops
Pharmacology Biochemistry and Behavior, 2014, Volume 119, Page 22
Deyar Asmaro, Patrick L. Carolan, and Mario Liotti
Addictive Behaviors, 2014, Volume 39, Number 1, Page 114

Comments (0)

Please log in or register to comment.