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Publication Date:
May 2006
ISSN:
1544-6115
DOI:
10.2202/1544-6115.1180

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Editor-in-Chief: Stumpf, Michael P.H.

Editorial Board Member: Beaumont, Mark / Binder, Harald / Gupta, Mayetri / Hubbard, Alan E. / Husmeier, Dirk / Ji, Hongkai / Keles, Sunduz / Kerr, Kathleen / Lazzeroni, Laura / Lin, Shili / Ma, Ping / Marjoram, Paul / Mertens, Bart / Nerman, Olle / G. Petretto, Enrico / Plagnol, Vincent / Purdom, Elizabeth / Robin, Stéphane / Rzhetsky, Andrey / Sanguinetti, Guido / van der Laan, Mark J. / von Haeseler, Arndt / Weeks, Daniel E. / Wiuf, Carsten / Zhao, Hongyu

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IMPACT FACTOR 2011: 1.517
5-year IMPACT FACTOR: 1.704
Rank 27 out of 116 in category Statistics & Probability in the 2011 Thomson Reuters Journal Citation Report/Science Edition

Cross-Validated Bagged Prediction of Survival

Sandra E. Sinisi / Romain Neugebauer / Mark J. van der Laan

1University of California, Berkeley

1Division of Biostatistics, School of Public Health, University of California, Berkeley

1Division of Biostatistics, School of Public Health, University of California, Berkeley

Citation Information: Statistical Applications in Genetics and Molecular Biology. Volume 5, Issue 1, Pages –, ISSN (Online) 1544-6115, DOI: 10.2202/1544-6115.1180, May 2006

Publication History:
Published Online:
2006-05-01

In this article, we show how to apply our previously proposed Deletion/Substitution/Addition algorithm in the context of right-censoring for the prediction of survival. Furthermore, we introduce how to incorporate bagging into the algorithm to obtain a cross-validated bagged estimator. The method is used for predicting the survival time of patients with diffuse large B-cell lymphoma based on gene expression variables.

Keywords: bootstrap aggregating; censoring; cross-validation; diffuse large-B-cell lymphoma; D/S/A algorithm

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