Association between eating behavior, anthropometric and biochemical measurements, and peptide YY (PYY) hormone levels in obese adolescents in outpatient care

Simone P. Fernandes 1 , 2 , Janine Alessi 1 , 2 , Zilda E. A. Santos 1 , 2 ,  and Elza D. de Mello 1 , 2
  • 1 Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
  • 2 Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
Simone P. Fernandes
  • Corresponding author
  • Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
  • Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
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, Janine Alessi
  • Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
  • Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
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, Zilda E. A. Santos
  • Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
  • Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
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and Elza D. de Mello
  • Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
  • Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
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Abstract

Objective

To evaluate the eating behavior of obese adolescents and its association with biochemical, anthropometric and peptide YY (PYY) measures.

Methods

Fifty-one obese adolescents received counseling for weight management at 12 monthly appointments. Fasting serum PYY levels, total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), triglycerides (TG), low density lipoprotein cholesterol (LDL-C), insulin and glucose levels, waist circumference (WC) and results from the Three-Factor Eating Questionnaire (TFEQ-21) were assessed.

Results

Over one year there was a significant increase in PYY levels (p = 0.026), reduction in TC (p = 0.003), TG (p = 0.022), BMI (p = 0.002), BMI z-score (p < 0.001) and WC (p = 0.003). During this period there was a decrease in the uncontrolled eating score (UE), illustrating that adolescents displayed more self-control (p = 0.008) at the end of the study; however, this result was independent of BMI and BMI z-score (p = 0.407). The reduction in UE was associated with a significant improvement in insulin levels (rs = 0.326; p = 0.020). The reduction in UE was also associated with lower levels of blood glucose (r = 0.332; p = 0.017), and the increase of cognitive restriction, with the reduction of insulin insulin (rs = −0.294; p = 0.036) and TG (r = −0.368; p = 0.008) and an increase in Cognitive Restraint.

Conclusions

Our results show that after a year of monitoring weight loss, adolescents had more controlled eating behaviors, increased PYY levels, and reduced weights.

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The Journal of Pediatric Endocrinology and Metabolism (JPEM) is the only international journal dedicated exclusively to endocrinology in the neonatal, pediatric and adolescent age groups, and publishes the results of clinical investigations in pediatric endocrinology and basic research. JPEM publishes Review Articles, Original Research, Case Reports, Short Communications and Letters to the Editor.

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