Comparison of strain and dyssynchrony measurements in fetal two-dimensional speckle tracking echocardiography using Philips and TomTec

Helen Ann Köster
  • Corresponding author
  • Department of Obstetrics and Gynecology, University Hospital of Münster, Münster, Germany
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, Kerstin Hammer
  • Department of Obstetrics and Gynecology, University Hospital of Münster, Münster, Germany
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, Janina Braun
  • Department of Obstetrics and Gynecology, University Hospital of Münster, Münster, Germany
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, Kathrin Oelmeier de Murcia
  • Department of Obstetrics and Gynecology, University Hospital of Münster, Münster, Germany
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, Mareike Möllers
  • Department of Obstetrics and Gynecology, University Hospital of Münster, Münster, Germany
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, Walter Klockenbusch
  • Department of Obstetrics and Gynecology, University Hospital of Münster, Münster, Germany
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and Ralf Schmitz
  • Corresponding author
  • Department of Obstetrics and Gynecology, University Hospital of Münster, Münster, Germany
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Abstract

Background

The aim of this study was to compare Philips and TomTec two-dimensional speckle tracking echocardiography (2D-STE) software measurements of strain and dyssynchrony values in healthy fetuses.

Methods

This was an explorative observational study in which the echocardiographic data of 93 healthy fetuses between the 20th and 38th week of gestation were determined from a four-chamber view using 2D speckle tracking. The global and segmental longitudinal strain values of both ventricles, inter-ventricular and left intra-ventricular dyssynchrony were analyzed using QLab version 10.8 (Philips Medical Systems, Andover, MA, USA) and TomTec-Arena version 2.30 (TomTec, Unterschleißheim, Germany).

Results

TomTec showed persistently lower values for all of the assessed strain and dyssynchrony variables. For all variables, the bias between vendors tended to increase with gestational age, though not to a significant extent. Left ventricular dyssynchrony and longitudinal strain within the mid segment of the septum correlated best between vendors; however, the limits of agreement were wide in both cases. None of the variables assessed in the two-chamber view compared well between QLAB and TomTec.

Conclusion

Speckle tracking software cannot be used interchangeably between vendors. Further investigations are necessary to standardize fetal 2D-STE.

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