Images not only show something, they also prompt the viewer to carry out the action they define. The increasing interaction between technologies, entities and objects via visual interfaces such as graphical user interfaces, touchscreens or augmented reality applications makes the viewer - first and foremost - a user. The actions of designing, navigating and intervening can only be carried out when the viewer has the relevant knowledge in connection with the image. In order to demonstrate the inseparable unity of the logic of visualization and action in image-controlled operations, interdisciplinary reflection is needed. Under the term 'Image Guidance', this volume discusses the aesthetic, operational and epistemic conditions under which visualizations become media of control and directions for action.