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The database offers a search function based on the EC classification up to 2018, containing 7 EC classes.
Since 1961 when International Union of Biochemistry approved the first Enzyme Classification, we classify enzymes based on the type of reactions they catalyse.

Click on the images to directly access the content from the related EC-class

Oxidoreductases Hydrolases Lyase Isomerases

Translocases (EC 7): A new EC Class!

In recent years further enzymatic studies supported the conclusion that enzymes that catalyse the movement of molecules across membranes aren't properly represented or classified.
Therefore, these enzymes will be now classified under a new EC class of translocases (EC 7) - enzymes which catalyse transport between 'side 1' and 'side 2' of a membrane.

The subclasses designate the types of ion or molecule translocated:

    EC 7.1 contains enzymes catalysing the translocation of H+,
    EC 7.2 contains those catalysing the translocation of inorganic cations and their chelates,
    EC 7.3 contains those catalysing the translocation of inorganic anions,
    EC 7.4 contains those catalysing the translocation of amino acids and peptides,
    EC 7.5 contains those catalysing the translocation of carbohydrates and their derivatives
    EC 7.6 contains those catalysing the translocation of other compounds.

The translocase activity of these enzymes is powered by and related to oxidoreductase reactions, the hydrolysis of a nucleoside triphosphate, the hydrolysis of a diphosphate, and decarboxylation reactions.