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Executive Editor – Helmut Sies

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Prof. em. Dr. med. Dr. h.c. Helmut Sies

Executive Editor
Prof. em. Dr. med. Dr. h.c. Helmut Sies

Vita & Research interests

Helmut Sies, M.D., Ph.D. (hon), M.D. (hon), FRCP, studied Medicine at the Universities of Tübingen, Paris and Munich. He was Full Professor and Chairman at the Institute of Biochemistry and Molecular Biology I at Heinrich-Heine-University Düsseldorf, Germany, where he is now a Research Professor. Member of the German National Academy of Sciences (Leopoldina). He was President of the Society for Free Radical Research International (SFRRI) and of the Oxygen Club of California (OCC). Fellow of the National Foundation for Cancer Research (NFCR), Bethesda. Senior Scientist at the Leibniz Institute for Research in Environmental Medicine. Helmut Sies has been a member of the Editorial Board of ‘Biological Chemistry’, and has been Editor-in-Chief of this Journal, where he now is an Executive Editor.

Research interests:

  • Oxidative Stress
  • Oxidants and Antioxidants
  • Hydroperoxide Metabolism
  • Glutathione
  • Micronutrients (Selenium, Polyphenols, Carotenoids)
  • Nutritional Biochemistry

Interview about his research interests (external video in German)



Extracellular localization of catalase is associated with the transformed state of malignant cells

Britta Böhm / Sonja Heinzelmann / Manfred Motz / Georg Bauer
DOI 10.1515/hsz-2014-0234

“This paper generates interest because of the concept of extracellular catalase as a hallmark of transformed cells.”

Alpha-synuclein at the intracellular and the extracellular side: functional and dysfunctional implications

Denis Ottolini / Tito Calí / Ildikò Szabò / Marisa Brini
DOI 10.1515/hsz-2016-0201

“This paper presents the various roles of alpha-synuclein in changing plasma membrane permeability and it discusses the basis for its involvement in neuronal degeneration.”

What can lipidomics tell us about the pathogenesis of Alzheimer disease?

Yanhui Xiang / Sin Man Lam / Guanghou Shui
DOI 10.1515/hsz-2015-0207

“The focus on lipids in pathophysiology is most welcome, given the predominant attention usually on proteins. It is important to recognize the fundamental role that lipids play in disease pathology.”

Mitochondrial carriers in inflammation induced by bacterial endotoxin and cytokines

Vito Iacobazzi / Vittoria Infantino / Alessandra Castegna / Alessio Menga / Erika Mariana Palmieri / Paolo Convertini / Ferdinando Palmieri
DOI 10.1515/hsz-2016-0260

“The role of metabolite carriers in physiology and pathophysiology is presented here for the mitochondrial inner and outer membrane. It is likely that the transport capacity is subject to regulation in disease states, as demonstrated here.”