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Journal of Basic and Clinical Physiology and Pharmacology

Editor-in-Chief: Horowitz, Michal

Editorial Board: Das, Kusal K. / Epstein, Yoram / S. Gershon MD, Elliot / Kodesh , Einat / Kohen, Ron / Lichtstein, David / Maloyan, Alina / Mechoulam, Raphael / Roth, Joachim / Schneider, Suzanne / Shohami, Esther / Sohmer, Haim / Yoshikawa, Toshikazu / Tam, Joseph

CiteScore 2016: 1.01

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Volume 26, Issue 3


Physiological characteristics of crab Portunus sanguinolentus egg mass extract from southeast coast of India

Subramanian Bragadeeswaran
  • Corresponding author
  • Assistant Professor, Faculty of Marine Sciences, Centre of Advanced Study in Marine Biology, Annamalai University, Parangipettai-608 502, Tamil Nadu, India
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Nadarajah Sri Kumaran
  • Department of Marine Biotechnology, AMET University, Kannathur, Chennai-603112, India
  • Faculty of Marine Sciences, Centre of Advanced Study in Marine Biology, Annamalai University, Parangipettai, Tamil Nadu, India
  • Other articles by this author:
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/ Lakshmanan Pandimuthu
  • Department of Biotechnology, J. J. College of Arts and Science, Pudukkottai, Tamil Nadu, India
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Rajagopal Prabahar
  • Faculty of Marine Sciences, Centre of Advanced Study in Marine Biology, Annamalai University, Parangipettai, Tamil Nadu, India
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2014-11-25 | DOI: https://doi.org/10.1515/jbcpp-2013-0133


Background: The present investigation was undertaken to evaluate the physiological characteristics of crab egg mass (Portunus sanguinolentus) crude extract.

Methods: Assays were followed by standard methods.

Results: A maximum of 256 hemolytic units (HU) and a minimum of 128 HU were found in chicken and goat erythrocytes. In an antimicrobial assay, Salmonella paratyphi and Aspergillus niger showed most susceptibility (8.0 mm and 13.0 mm) against n-butanol extracts. In the tail flick method, 5.33±0.19* AR the maximum analgesic response was recorded 30 min after the administration of crude extract (150 mg kg–1). In the hot plate method, 5.13±0.13* AR maximum paw licking was recorded 15 min after the administration of crude extract (150 mg kg–1). In an anti-inflammatory assay, 0.31±0.23* anti-inflammatory response and inhibition of paw edema 39.22% were observed 1 h after the administration of crude extract (250 mg kg–1). Primary structural groups gained through Fourier transformed infrared (FTIR) analysis peaks were observed and assigned as amide groups I (1517.81–1633.12 cm–1), II (1446.58–1517.81 cm–1) and III (1342.47–1406.85 cm–1).

Conclusions: The results indicate that crab egg masses have remarkable antimicrobial, hemolytic and cytotoxic activities.

Keywords: analgesic; antibacterial; antifungal; anti-inflammatory; crab egg mass; hemolytic


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About the article

Corresponding author: Dr. Subramanian Bragadeeswaran, Assistant Professor, Faculty of Marine Sciences, Centre of Advanced Study in Marine Biology, Annamalai University, Parangipettai-608 502, Tamil Nadu, India, Phone: +91-4144-243223, Ext: 269, Fax: +91-4144-243555, Mobile: +91-9894823364, E-mail:

Received: 2013-09-10

Accepted: 2014-10-21

Published Online: 2014-11-25

Published in Print: 2015-05-01

Citation Information: Journal of Basic and Clinical Physiology and Pharmacology, Volume 26, Issue 3, Pages 265–273, ISSN (Online) 2191-0286, ISSN (Print) 0792-6855, DOI: https://doi.org/10.1515/jbcpp-2013-0133.

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