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Licensed Unlicensed Requires Authentication Published by De Gruyter July 1, 2012

Endpoints in animal pain models

  • Andrew S.C. Rice
  1. Funding: Wellcome Trust (London Pain Consortium), Innovative Medicines Initiative – EUROPAIN (European Commission and selected EFPIA members) and Derek Butler Trust.

Recommended reading

[1] Rice ASC. Predicting analgesic efficacy from animal models of peripheral neuropathy and nerve injury: a critical view from the clinic. In: Mogil JS, editor. Pain 2010—an updated review: refresher course syllabus. Seattle: IASP Press; 2010. p. 415–426.Search in Google Scholar

[2] Andrews N, et al. Spontaneous burrowing behaviour in the rat is reduced by peripheral nerve injury or inflammation associated pain. European Journal of Pain 2012;16:485–95.10.1016/j.ejpain.2011.07.012Search in Google Scholar PubMed

[3] Hasnie FS, et al. Further characterization of a rat model of varicella zoster virus-associated pain: relationship between mechanical hypersensitivity and anxiety-related behavior, and the influence of analgesic drugs. Neuroscience 2007;144(4):1495–508.10.1016/j.neuroscience.2006.11.029Search in Google Scholar PubMed PubMed Central

[4] Wallace VCJ, et al. Anxiety-like behaviour is attenuated by gabapentin, morphine and diazepam in a rodent model of HIV anti-retroviral-associated neuropathic pain. Neuroscience Letters 2008;448(1):153–6.10.1016/j.neulet.2008.10.005Search in Google Scholar PubMed PubMed Central

[5] Wallace VCJ, et al. Characterisation of rodent models of HIV-gp120 and antiretroviral associated neuropathic pain. Brain 2007;130(10):2688–702.10.1093/brain/awm195Search in Google Scholar PubMed PubMed Central

[6] Wallace VCJ, et al. Pharmacological, behavioural and mechanistic analysis of HIV-1 gp120 induced painful neuropathy. Pain 2007;133(1–3):47–63.10.1016/j.pain.2007.02.015Search in Google Scholar PubMed PubMed Central

[7] Sena ES, et al. How can we improve the pre-clinical development of drugs for stroke? Trends in Neurosciences 2007;30(9):433–9.10.1016/j.tins.2007.06.009Search in Google Scholar PubMed

[8] Sena ES, et al. Publication bias in reports of animal stroke studies leads to major overstatement of efficacy. PLoS Biology 2010;8(3):e1000344.10.1371/journal.pbio.1000344Search in Google Scholar PubMed PubMed Central

[9] Rice ASC, et al. Animal models and the prediction of efficacy in clinical trials of analgesic drugs: a critical appraisal and call for uniform reporting standards. Pain 2008;139(2):243–7.10.1016/j.pain.2008.08.017Search in Google Scholar PubMed

[10] Macleod MM, et al. Good laboratory practice. Preventing introduction of bias at the bench. Stroke 2009;40(3):e50–2.10.1161/STROKEAHA.108.525386Search in Google Scholar PubMed

[11] Kilkenny C, et al. Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. PLoS Biology 2010;8(6):e1000412.10.1371/journal.pbio.1000412Search in Google Scholar PubMed PubMed Central

Published Online: 2012-07-01
Published in Print: 2012-07-01

© 2012 Scandinavian Association for the Study of Pain

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