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Publicly Available Published by De Gruyter September 27, 2011

Chlorine-free copper-catalyzed oxidative synthesis of 1,3,4-oxadiazoles with molecular oxygen as the sole oxidant

  • Huanfeng Jiang , Xianwei Li , Xiaoyan Pan and Peng Zhou

Chlorine-free is not only one of the new concepts of green chemistry, but also a problematical task for chemical processes in industrial utility. During the past several decades, we devoted ourselves to the study of chlorine-free organic synthesis. Herein, we describe an efficient chlorine-free copper-catalyzed oxidative approach providing 1,3,4-oxadiazoles in good yields from readily available starting materials. This transformation requires only a green and inexpensive reagent to afford the structurally useful motifs, and has a broad functional groups tolerance.


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Online erschienen: 2011-9-27
Erschienen im Druck: 2011-9-27

© 2013 Walter de Gruyter GmbH, Berlin/Boston

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