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Publicly Available Published by De Gruyter January 1, 2009

Modeling genome structure and function

  • Ram Samudrala


The ongoing genomics revolution has led to the creation and enumeration of all the genes encoded within several organisms. The next steps are to catalog all proteins, their structures, and their functions in different contexts. At the same time, scientists have been pursuing experimental and theoretical approaches to integrate this information to gain understanding of the behavior of entire systems. In this work, we provide a framework for obtaining structures for all tractable protein sequences encoded by a genome, and using the resulting structures to aid in understanding function. Our aim is to integrate the output produced with other genomic and proteomic data to create a comprehensive picture of systems and organismal biology.


International Conference on Bioinformatics 2002: North-South Networking, Bangkok, Thailand, 2002-02-06–2002-02-08

Published Online: 2009-01-01
Published in Print: 2002-01-01

© 2013 Walter de Gruyter GmbH, Berlin/Boston

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