Biomedical Chemistry: Current Trends and Developments

Nuno Vale

Open Access Published by De Gruyter Open Poland 2015

Biomedical Chemistry

Current Trends and Developments

Nuno Vale

https://doi.org/10.1515/9783110468755

Overview
Contents

About this book

Biomedical Chemistry provides readers with an understanding of how fundamental chemical concepts are used to combat some diseases. The authors explain the interdisciplinary relationship of chemistry with biology, physics, pharmacy and medicine. The results of chemical research can be applied to understand chemical processes in cells and in the body, and new methods for drug transportation. Also, basic chemical ideas and determination of disease etiology are approached by developing techniques to ensure optimum interaction between drugs and human cells. This Book is an excellent resource for students and researchers in health-related fields with frontier topics in medicinal and pharmaceutical chemistry, organic chemistry and biochemistry.

Chemistry and Diseases, Drug Discovery and Design, Nanotechnology

Author information

Nuno Vale, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Portugal

Topics

Frontmatter Publicly Available Download PDF	I
Contents Publicly Available Download PDF	V
Preface Publicly Available Download PDF	XI
Section 1: Chemical Principles in Drug Design and Discovery
1.1 Functional Groups of Biomolecules and their Reactions Diana C. G. A. Pinto, João M. P. Pereira and Artur M. S. Silva Publicly Available Download PDF	2
1.2 Designing Covalent Inhibitors: A Medicinal Chemistry Challenge Francisca Lopes, Maria M. M. Santos and Rui Moreira Publicly Available Download PDF	44
Section 2: Chemical Basis of Drug Action and Diseases
2.1 Pharmacokinetics and Bioanalysis to Improve Drug Development Ana Fortuna, Gilberto Alves and Amílcar Falcão Publicly Available Download PDF	62
2.2 Translational Research in Endocrinology and Neuroimmunology Applied to Depression Ma-Li Wong, Martin Lewis and Julio Licinio Publicly Available Download PDF	119
2.3 Understanding the Metabolic Syndrome Using a Biomedical Chemistry Profile Cidália Pereira, Rosário Monteiro and Maria João Martins Publicly Available Download PDF	132
2.4 Brain Neurochemistry and Cognitive Performance: Neurotransmitter Systems Andrea Lobo and Teresa Summavielle Publicly Available Download PDF	148
Section 3: Strategies to Develop New and Better Drugs
3.1 Amino Acids and Peptides in Medicine: Old or New Drugs? Nuno Vale Publicly Available Download PDF	178
3.2 Targeting Calcium-mediated Excitotoxicity in the CNS James J. Chambers Publicly Available Download PDF	229
3.3 Strategies for Conversion of Peptides to Peptidomimetic Drugs Rebecca Fransson, Christian Sköld and Anja Sandström Publicly Available Download PDF	245
3.4 Synthetic Vs. Natural Bioactive Compounds Against Tropical Disease Brandon S. Pybus Publicly Available Download PDF	275
3.5 Current Trends and Developments for Nanotechnology in Cancer Mónica Ferreira, Patrick Almeida, Mohammad-Ali Shahbazi, Alexandra Correia and Hélder A. Santos Publicly Available Download PDF	290
Index Publicly Available Download PDF	343

(Deutsch)

Language: English
Publisher: De Gruyter Open Poland
Audience: Students and researchers in health-related fields: organic, medicinal and pharmaceutical chemistry and biochemistry.
Pages
- Main content: 361
Illustrations
- Illustrations: 36
- Coloured Illustrations: 94
- Tables: 25
- Coloured Tables: 2
Keywords: medicinal chemistry; natural products; drug design; drug discovery; translational research

eBook

Published: February 22, 2016
ISBN: 9783110468755

Hardcover

Published: February 22, 2016
ISBN: 9783110468748