Active Pharmaceutical Ingredient Manufacturing: Nondestructive Creation

Girish K. Malhotra

Published by De Gruyter 2022

Active Pharmaceutical Ingredient Manufacturing

Nondestructive Creation

Girish K. Malhotra

In the series De Gruyter STEM

https://doi.org/10.1515/9783110702842

Overview
Contents

About this book

The book reviews the history of current brand and generic business in pharmaceuticals manufacturing practices. Based on examples, the reader can interpolate, extrapolate and exploit mutual behavior (physical and chemical properties) of chemicals to design and commercialize processes that fulfi ll the demands, also manipulate chemical unit processes and unit operations to reduce/minimize effl uents and lower environmental impact i.e. reduce global warming. Readers will be able to simplify process development, design and commercialize economic manufacturing processes.

Of interest to fine and specialty chemicals, including active pharmaceutical ingredients, additives for plastics, coatings, flavor, fragrance, and food industry.

With examples of processes that could be commercialized to produce API continuously.

Author / Editor information

Girish K. Malhotra, EPCOT International, Pepper Pike, Ohio, USA.

Topics

Frontmatter Publicly Available Download PDF	I
Preface Publicly Available Download PDF	VII
Contents Publicly Available Download PDF	XI
Chapter 1 History of pharmaceuticals Requires Authentication Unlicensed Licensed Download PDF	1
Chapter 2 Business model: brand versus generics, product demand, process selection, and economics Requires Authentication Unlicensed Licensed Download PDF	41
Chapter 3 Physical and chemical properties Requires Authentication Unlicensed Licensed Download PDF	69
Chapter 4 Pharma chemistry/chemical development Requires Authentication Unlicensed Licensed Download PDF	89
Chapter 5 Manufacturing process development and case studies Requires Authentication Unlicensed Licensed Download PDF	125
Chapter 6 Active pharmaceutical ingredients (API): innovation, design considerations, and waste reduction Requires Authentication Unlicensed Licensed Download PDF	177
Chapter 7 Process documentation and operating strategies Requires Authentication Unlicensed Licensed Download PDF	213
Chapter 8 Road Map Requires Authentication Unlicensed Licensed Download PDF	277
Index Requires Authentication Unlicensed Licensed Download PDF	309

(Deutsch)

Language: English
Publisher: De Gruyter
Audience: Chemists, Chemical Engineers, Process Developers, Designers, Operating and Management Personnel, Financial Controllers.
Pages
- Front matter: 16
- Main content: 317
Illustrations
- Illustrations: 114
- Coloured Illustrations: 20
- Tables: 84
Keywords: Active Pharmaceutical Ingredient; Pharmaceutical Manufacturing; Drug Regulations; Pharmaceiticals

eBook

Published: April 19, 2022
ISBN: 9783110702842

Paperback

Published: May 3, 2022
ISBN: 9783110702828